Table 2.
Effect of ARA290 Treatment on Akita and Control Mouse Metabolic Parameters
| Experimental Group | HbA1c (%) | Body Weight (g) | Blood Glucose (mg%) |
|---|---|---|---|
| Saline Treated Akita (n=8 ) | 9.3 ± 0.6a | 21.5 ± 0.7a | 597 ± 3a |
| ARA290 Treated Akita (n=8 ) | 9.6 ± 0.5a | 22.0 ± 0.6a | 595 ± 5a |
| Combined Saline + ARA290 Treated Controls (n=18 ) | 4.0 ± 0.1 | 31.3 ± 0.6 | 203 ± 13 |
| Akita 4 month diabetic (starting point of treatment) (n=4) | --- | 24.7 ± 1.1 | 560 ± 19 |
Values represent the means ± SEM of n mice.
Statistical Comparison:
a
p≤0.001 vs. control