Table 1.

Clinical Characteristics and Cerebrovascular Disease Pathology of the Cohort

Variable	Mean (SD) or N (%)
Age at Death (years)	88.5 (5.38)
Sex (female)	256 (61.2%)
White, non-Hispanic (N, %)	403 (96.3%)
Education (years)	13.9 (3.14)
Last MMSE (max 30)	22.7 (8.86)
Dementia (N, %)	188 (45%)
Depressive Symptoms (max 10)	1.6 (1.91)
Global Parkinsonian sign score (max 100)	18.6 (14.77)
Parkinsonian gait (max 100)	41.5 (23.49)
Rigidity (max 100)	11.7 (21.10)
Bradykinesia (max 100)	21.4 (20.37)
Tremor (max 100)	5.2 (11.67)
Summary of Self-Report Medical Conditions	1.7 (1.2)
Cancer	180 (43.1%)
Hypertension	159 (38.3%)
Stroke	108 (25.8%)
Myocardial Infarction	102 (24.4%)
Thyroid	86 (20.6%)
Diabetes	39 ( 9.4%)
Head Injury	31 ( 7.4%)
Cerebrovascular Pathologies
Macroscopic Infarcts	N=150 (35.9%)
Location- Cortical      Subcortical	48 (11.5%) 124 (29.7%)
Number per case– N (%)	1–78(18.7%); 2–37(8.9%); 3–18(4.3%); 4–10(2.4%); ≥5– 7 (1.7%)
Microscopic Infarcts	N=125 (29.9%)
Location - Cortical      Subcortical	53 (12.7%) 79 (18.9%)
Number per case – N (%)	1–77 (18.4%); 2–30 (7.2%); 3–13(3.1%); 4–4(1.9%); ≥5–1 (0.2%);
Arteriolosclerosis
None, Possible or Minimal  Mild  Moderate  Severe	245 (58.7%) 117 (28.0%) 43 (10.3%) 13 ( 3.1%)