Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ibandronate pharmacodynamic parameter estimates for urine CTX in postmenopausal women with osteopenia, using integrated bone homeostasis model.
| Parameter (units) | Final Estimate | CV% |
|---|---|---|
| DA (day−1) | 0.842 | 15.2 |
| Imax | 1 a | - |
| h | 2 b | - |
| IC50 (ng/L) | 522 | 8.74 |
| Eb,uCTX (μg/mmolCr) | 31 | 28.7 |
| n (dimensionless) | 5 b | - |
fixed parameter based on indirect response model theory [22].
fixed parameter based on preliminary analysis.
