Appendix I. The association and discriminatory ability of criteria variables for remission criteria.

	ARCK	VARA
AE 3 ESR	AUC (Harrell's c)	AUC (Harrell's c)
SJC ≤1	0.77 (0.76, 0.79)	0.75 (0.74, 0.76)
TJC ≤1	0.75 (0.74, 0.77)	0.76 (0.74, 0.77)
PtGlobal ≤1	0.96 (0.96, 0.97)	0.94 (0.93, 0.95)
ESR <20,<30	0.67 (0.66, 0.69)	0.77 (0.75, 0.78)
SJC ≤1 &TJC ≤1	0.85 (0.84, 0.87)	0.83 (0.81, 0.84)
SJC ≤1 &TJC ≤1 + ESR	0.90 (0.89, 0.91)	0.92 (0.91, 0.93)
AE 3
SJC ≤1	0.77 (0.76, 0.79)	0.76 (0.75, 0.78)
TJC ≤1	0.76 (0.74, 0.77)	0.77 (0.76, 0.78)
PtGlobal ≤1	0.97 (0.97, 0.98)	0.96 (0.95, 0.97)
SJC ≤1 &TJC ≤1	0.86 (0.84, 0.87)	0.84 (0.83, 0.85)
SJC ≤1 &TJC ≤1 + ESR	0.80 (0.75, 0.84)	0.70 (0.66, 0.74)
AE 4
SJC ≤1	0.77 (0.75, 0.78)	0.76 (0.74, 0.77)
TJC ≤1	0.75 (0.74, 0.76)	0.76 (0.75, 0.78)
PtGlobal ≤1	0.96 (0.95, 0.97)	0.95 (0.94, 0.96)
PhGlobal ≤1	0.93 (0.92, 0.94)	0.93 (0.92, 0.94)
SJC ≤1 &TJC ≤1	0.85 (0.83, 0.86)	0.83 (0.82, 0.85)
SJC ≤1 &TJC + ESR	0.81 (0.76, 0.86)	0.71 (0.67, 0.76)
AE CDAI
SJC ≤1	0.77 (0.76, 0.79)	0.76 (0.74, 0.78)
TJC ≤1	0.76 (0.74, 0.77)	0.77 (0.75, 0.78)
PtGlobal ≤1	0.78 (0.73, 0.84)	0.85 (0.82, 0.89)
PhGlobal ≤1	0.90 (0.87, 0.93)	0.88 (0.85, 0.90)
SJC ≤1 &TJC ≤1	0.86 (0.84, 0.87)	0.83 (0.82, 0.85)
SJC ≤1 &TJC ≤1 + ESR	0.79 (0.75, 0.84)	0.72 (0.68, 0.76)
AE SDAI
SJC ≤1		0.74 (0.71, 0.76)
TJC ≤1		0.75 (0.73, 0.78)
PtGlobal ≤1		0.88 (0.84, 0.91)
PhGlobal ≤1		0.86 (0.82, 0.89)
SJC ≤1 &TJC ≤1		0.81 (0.78, 0.83)
CRP ≤1		0.61 (0.58, 0.64)
AE CRP
SJC ≤1		0.75 (0.73, 0.77)
TJC ≤1		0.76 (0.74, 0.77)
PtGlobal ≤1		0.95 (0.94, 0.96)
SJC ≤1 &TJC ≤1		0.83 (0.81, 0.84)
SJC ≤1 &TJC ≤1 + ESR		0.71 (0.65, 0.76)
CRP ≤1		0.65 (0.64, 0.67)

See methods for criteria definition.