Table 5. Main and Interaction Effects for Dichotomous Genetic Risk Models for Disorganization Scores in Generation R and SECCYD.
| Gene | Risk model | Generation R | NICHD SECCYD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| B | SE | β | p | B | SE | β | p | ||
| Disorganization | |||||||||
|
| |||||||||
| DRD2 | T (A1) | ||||||||
| DRD2 | .28 | .18 | .07 | .13 | .24 | .19 | .06 | .19 | |
| Sensitivity | -.15 | .13 | -.07 | .23 | -.03 | .09 | -.02 | .71 | |
| Sens*DRD2 | .08 | .21 | .02 | .69 | .24 | .14 | .09 | .09 | |
| DRD4 | 7 + | ||||||||
| DRD4 | -.19 | .18 | -.05 | .30 | .36 | .23 | .07 | .12 | |
| Sensitivity | -.09 | .13 | -.04 | .46 | .00 | .08 | .00 | .99 | |
| Sens*DRD4 | -.09 | .22 | -.02 | .68 | .17 | .17 | .05 | .34 | |
| COMT | homozygous | ||||||||
| COMT | -.52 | .17 | -.14 | <.01 | -.35 | .18 | -.09 | .04 | |
| Sensitivity | .06 | .14 | .03 | .66 | .09 | .11 | .06 | .42 | |
| Sens*COMT | -.41 | .20 | -.12 | .04 | -.05 | .14 | -.03 | .70 | |
| 5-HTT | short | ||||||||
| 5-HTT | -.05 | .18 | -.01 | .77 | -.15 | .20 | -.03 | .45 | |
| Sensitivity | -.14 | .18 | -.06 | .45 | .24 | .12 | .15 | .05 | |
| Sens*5-HTT | -.01 | .22 | .00 | .97 | -.26 | .15 | -.14 | .08 | |
| OXTR (rs53576) | A | ||||||||
| OXTR | -.27 | .17 | -.07 | .11 | -.21 | .18 | -.05 | .25 | |
| Sensitivity | -.17 | .17 | -.07 | .30 | .07 | .11 | .04 | .54 | |
| Sens*OXTR | .05 | .21 | .02 | .81 | .02 | .14 | .01 | .90 | |
| OXTR (rs2254298) | A | ||||||||
| OXTR | .14 | .20 | .03 | .50 | .16 | .22 | .03 | .48 | |
| Sensitivity | -.11 | .11 | -.05 | .33 | .03 | .08 | .02 | .67 | |
| Sens*OXTR | -.18 | .24 | -.04 | .47 | .09 | .16 | .03 | .59 | |
Note. Dichotomous risk models. B denotes change in security scores per unit change in the predictor.