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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Stroke. 2011 Sep 22;42(11):3075–3079. doi: 10.1161/STROKEAHA.111.623157

Table 3.

Incidence Rates and Multivariate-Adjusted Hazard Ratios and 95% Confidence Intervals (95% CI) of Intracerebral Hemorrhage (ICH) According to Left Ventricular Hypertrophy (ECG-LVH), ARIC and CHS

ECG-LVH (MN Codes) ECG-LVH (Cornell Criteria)


No Yes No Yes
ARIC n ICH/N at risk 64/12,843 5/236 62/12,817 7/262
Incidence Rate* 2.9 15.3 2.8 18.2
Model 1 Hazard Ratio 1.0 2.77 1.0 3.67
95% CI -- 1.09–7.06 -- 1.64–8.20
Model 2 Hazard Ratio 1.0 2.00 1.0 2.79
95% CI -- 0.76–5.25 -- 1.22–6.41
CHS n ICH/N at risk 87/4,842 6/234 86/4,814 7/262
Incidence Rate* 14.5 27.2 14.4 26.5
Model 1 Hazard Ratio 1.0 2.02 1.0 1.98
95% CI -- 0.87–4.68 -- 0.91–4.31
Model 2 Hazard Ratio 1.0 1.63 1.0 1.69
95% CI -- 0.69–3.83 -- 0.77–3.71
ARIC + CHS n ICH/N at risk 151/17,685 11/470 148/17,631 14/524
Incidence Rate* 5.3 20.1 5.2 21.6
Model 1 Hazard Ratio 1.0 2.25 1.0 2.53
95% CI -- 1.20–4.22 -- 1.45–4.43
Model 2 Hazard Ratio 1.0 1.73 1.0 2.07
95% CI -- 0.91–3.28 -- 1.18–3.65
*

Crude incidence rate per 10,000 person-years

Adjusted for age (continuous), race (African American, white), current smoking (yes, no), LDL cholesterol (continuous), natural log triglycerides (continuous), and fibrinogen (continuous).

Adjusted for Model 1 variables plus systolic blood pressure (continuous)