Table 1.
Characteristica | Total Population (n = 529) |
CKD Diagnosis |
P for Differenceb | |||||||
Glomerular CKD (n = 109 (21%)) |
Nonglomerular CKD (n = 420 (79%)) |
|||||||||
No. of Cases | % | Median (IQR) | No. of Cases | % | Median (IQR) | No. of Cases | % | Median (IQR) | ||
Age, years | 11 (7 to 14) | 14 (11 to 16) | 10 (6 to 14) | <0.01 | ||||||
Female sex | 203 | 38 | 52 | 48 | 151 | 36 | 0.03 | |||
Race | <0.01 | |||||||||
White | 354 | 67 | 58 | 53 | 296 | 70 | ||||
African American | 116 | 22 | 37 | 34 | 79 | 19 | ||||
Other | 59 | 11 | 14 | 13 | 45 | 11 | ||||
Hispanic ethnicity | 77 | 15 | 19 | 17 | 58 | 14 | 0.36 | |||
Duration of CKD, years | 6.4 (3.1 to 10.3) | 3.8 (1.7 to 7.4) | 7.1 (3.5 to 10.8) | <0.01 | ||||||
Number of GFR measurements per subject | 0.35 | |||||||||
2 | 59 | 11 | 17 | 16 | 41 | 10 | ||||
3 | 156 | 29 | 35 | 32 | 121 | 29 | ||||
4 | 173 | 33 | 32 | 29 | 141 | 34 | ||||
5 | 118 | 22 | 22 | 20 | 96 | 23 | ||||
6 | 24 | 5 | 3 | 3 | 21 | 5 | ||||
Years of follow-up | 3.0 (2.1 to 3.9) | 2.8 (1.8 to 3.7) | 3.0 (2.1 to 3.9) | <0.01 | ||||||
GFR level, mL/minute/1.73 m2 | 44 (33 to 57) | 48 (34 to 63) | 44 (33 to 55) | 0.04 | ||||||
Annualized percentage change in GFR, % per year | −4.7 (−13.1 to 1.7) | −10.5 (−23.4 to −1.2) | −3.9 (−11.4 to 2.2) | <0.01 |
Abbreviations: CKD, chronic kidney disease; GFR, glomerular filtration rate; IQR, interquartile range.
At baseline, unless otherwise indicated.
Based on Wilcoxon rank-sum test for continuous variables and Fisher’s exact test for categorical variables.