Table 2.
Smoking Characteristic | Person-Years | Reference Category Included Household Passive Smokers |
Reference Category Excluded Household Passive Smokers |
||||
No. of Cases | RR | 95% CI | No. of Cases | RR | 95% CI | ||
Smoking status | |||||||
Never smoker | 880,841b | 374 | 1.00 | Referent | 87 | 1.00 | Referent |
Ever smoker | 442,299 | 252 | 1.11 | 0.94, 1.30 | 252 | 1.22 | 0.95, 1.57 |
Former smoker | 377,384 | 224 | 1.14 | 0.96, 1.35 | 224 | 1.25 | 0.97, 1.61 |
Current smoker | 64,915 | 28 | 0.91 | 0.62, 1.34 | 28 | 1.00 | 0.65, 1.54 |
Ever-smoking dose response | |||||||
Smoking intensity, cigarettes/day | |||||||
<10 | 204,166 | 103 | 1.02 | 0.82, 1.27 | 103 | 1.12 | 0.84, 1.50 |
10–19 | 132,589 | 83 | 1.19 | 0.93, 1.51 | 83 | 1.30 | 0.96, 1.77 |
≥20 | 95,024 | 64 | 1.28 | 0.98, 1.68 | 64 | 1.41 | 1.01, 1.96 |
P for trend | 0.04 | 0.02 | |||||
Total no. of smoking years | |||||||
≤10 | 132,703 | 53 | 1.06 | 0.79, 1.41 | 53 | 1.16 | 0.82, 1.65 |
11–20 | 106,546 | 50 | 1.01 | 0.75, 1.36 | 50 | 1.11 | 0.78, 1.58 |
>20 | 172,375 | 136 | 1.20 | 0.98, 1.47 | 136 | 1.32 | 1.00, 1.74 |
P for trend | 0.09 | 0.06 | |||||
No. of smoking pack-years | |||||||
≤10 | 219,822 | 105 | 1.07 | 0.86, 1.33 | 105 | 1.17 | 0.88, 1.57 |
11–20 | 76,733 | 41 | 1.01 | 0.73, 1.40 | 41 | 1.12 | 0.77, 1.63 |
>20 | 107,407 | 91 | 1.32 | 1.04, 1.67 | 91 | 1.45 | 1.07, 1.96 |
P for trend | 0.03 | 0.02 | |||||
Age of smoking initiation, years | |||||||
<18 | 128,612 | 75 | 1.33 | 1.04, 1.72 | 75 | 1.47 | 1.07, 2.01 |
≥18 | 283,012 | 164 | 1.04 | 0.87, 1.26 | 164 | 1.15 | 0.88, 1.50 |
No. of years since quitting smoking among former smokers | |||||||
>20 | 156,813 | 125 | 1.27 | 1.03, 1.56 | 125 | 1.40 | 1.05, 1.85 |
11–20 | 106,882 | 54 | 1.11 | 0.83, 1.49 | 54 | 1.23 | 0.87, 1.73 |
≤10 | 87,618 | 37 | 0.98 | 0.69, 1.37 | 37 | 1.07 | 0.73, 1.59 |
Abbreviations: CI, confidence interval; RR, relative risk.
All models were stratified by age at cohort entry and adjusted for race (non-Hispanic white or other) and alcohol consumption 1 year before cohort entry (0 g/day, <15 g/day, ≥15 g/day, or unknown).
bPerson-years of follow-up for never smokers excluding household passive smokers were 255, 211.