Appendix Table 1.
Relative Risk of Different Types of Non-Hodgkin Lymphoma by Smoking Status Among Women in the California Teachers Study, 1995–2007a
| Smoking Characteristic | Diffuse Large B-Cell Lymphoma |
Follicular Lymphoma |
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma |
||||||
| No. of Cases | RR | 95% CI | No. of Cases | RR | 95% CI | No. of Cases | RR | 95% CI | |
| Smoking status | |||||||||
| Never smoker with no passive exposure | 27 | 1.00 | Referentb | 14 | 1.00 | Referentb | 17 | 1.00 | Referentb |
| Ever smoker | 60 | 1.00 | 0.62, 1.60 | 44 | 1.44 | 0.77, 2.66 | 54 | 1.08 | 0.62, 1.89 |
| Former smoker | 52 | 1.00 | 0.62, 1.62 | 36 | 1.36 | 0.72, 2.57 | 51 | 1.17 | 0.67, 2.06 |
| Current smoker | 8 | 0.99 | 0.44, 2.20 | 8 | 1.90 | 0.79, 4.60 | 3 | 0.46 | 0.13, 1.58 |
| Ever-smoking dose response | |||||||||
| Smoking intensity, cigarettes/day | |||||||||
| <10 | 21 | 0.78 | 0.44, 1.41 | 18 | 1.34 | 0.66, 2.74 | 23 | 1.05 | 0.55, 1.99 |
| 10–19 | 20 | 1.08 | 0.60, 1.96 | 18 | 1.90 | 0.93, 3.89 | 17 | 1.10 | 0.56, 2.19 |
| ≥20 | 18 | 1.36 | 0.74, 2.51 | 8 | 1.16 | 0.48, 2.79 | 13 | 1.17 | 0.56, 2.45 |
| P for trend | 0.37 | 0.62 | 0.75 | ||||||
| Total no. of smoking years | |||||||||
| ≤10 | 11 | 0.86 | 0.42, 1.76 | 12 | 1.61 | 0.74, 3.53 | 9 | 1.16 | 0.62, 2.19 |
| 11–20 | 13 | 1.00 | 0.51, 1.96 | 5 | 0.72 | 0.26, 2.03 | 15 | 0.89 | 0.38, 2.08 |
| >20 | 34 | 1.13 | 0.67, 1.91 | 22 | 1.51 | 0.76, 3.02 | 27 | 1.12 | 0.57, 2.20 |
| P for trend | 0.44 | 0.20 | 0.89 | ||||||
| No. of smoking pack-years | |||||||||
| ≤10 | 20 | 0.78 | 0.43, 1.41 | 19 | 1.38 | 0.68, 2.79 | 24 | 0.92 | 0.41, 2.08 |
| 11–20 | 11 | 1.05 | 0.51, 2.13 | 9 | 1.66 | 0.71, 3.88 | 8 | 1.44 | 0.71, 2.92 |
| >20 | 26 | 1.42 | 0.81, 2.49 | 11 | 1.21 | 0.54, 2.72 | 18 | 1.01 | 0.54, 1.89 |
| P for trend | 0.05 | 0.67 | 0.90 | ||||||
| Age at smoking initiation, years | |||||||||
| <18 | 24 | 1.65 | 0.94, 2.90 | 15 | 1.84 | 0.87, 3.85 | 12 | 1.02 | 0.48, 2.16 |
| ≥18 | 34 | 0.82 | 0.49, 1.38 | 24 | 1.15 | 0.59, 2.27 | 39 | 1.11 | 0.62, 1.99 |
| No. of years since quitting smoking among former smokers | |||||||||
| ≤10 | 5 | 0.50 | 0.19, 1.30 | 7 | 1.32 | 0.53, 3.30 | 7 | 0.89 | 0.36, 2.16 |
| 11–20 | 16 | 1.28 | 0.68, 2.41 | 10 | 1.48 | 0.65, 3.37 | 9 | 0.88 | 0.39, 1.99 |
| >20 | 30 | 1.16 | 0.68, 1.98 | 17 | 1.33 | 0.64, 2.74 | 33 | 1.44 | 0.79, 2.62 |
Abbreviations: CI, confidence interval; RR, relative risk.
a
All models were stratified by age at cohort entry and adjusted for race (non-Hispanic white or other) and alcohol consumption 1 year before cohort entry (0 g/day, <15 g/day, ≥15 g/day, or unknown).
b
Reference category excluded household passive smokers.