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. 2011 Jun 9;174(3):345–353. doi: 10.1093/aje/kwr096

Table 2.

Estimated Risk Difference for Uncontrolled Asthma According to Treatment Group (Daily Use or Periodic Use of Inhaled Corticosteroids) Among Children With Mild Persistent Asthma, Parent Asthma Communication Experience Study, 2007–2008a

c1 s1 r = 1.0
 r = 1.5
 r = 2.0
RD 95% BCIb RD 95% BCI RD 95% BCI
0.00 0.00 0.20 0.12, 0.30 0.20 0.12, 0.30 0.20 0.12, 0.30
0.05 0.18 0.10, 0.28 0.18 0.10, 0.28 0.17 0.09, 0.28
0.10 0.16 0.08, 0.27 0.15 0.07, 0.26 0.14 0.06, 0.25
0.20 0.12 0.05, 0.23 0.10 0.03, 0.22 0.08 0.01, 0.20
0.30 0.08 0.01, 0.20 0.05 −0.02, 0.18 0.02 −0.05, 0.15
0.05 0.00 0.16 0.08, 0.27 0.15 0.07, 0.26 0.14 0.07, 0.25
0.05 0.14 0.06, 0.25 0.13 0.05, 0.24 0.11 0.04, 0.22
0.15 0.10 0.03, 0.22 0.08 0.00, 0.20 0.05 −0.02, 0.17
0.25 0.06 −0.01, 0.18 0.03 −0.05, 0.15 −0.01 −0.08, 0.12
0.10 0.00 0.12 0.05, 0.23 0.10 0.03, 0.22 0.08 0.01, 0.20
0.10 0.08 0.01, 0.20 0.05 −0.02, 0.17 0.02 −0.05, 0.15
0.20 0.04 −0.03, 0.16 0.00 −0.07, 0.13 −0.04 −0.11, 0.10
0.20 0.00 0.04 −0.03, 0.16 0.00 −0.07, 0.13 −0.04 −0.11, 0.09
0.10 0.00 −0.07, 0.13 −0.05 −0.12, 0.09 −0.10 −0.17, 0.04
0.30 0.00 −0.05 −0.10, 0.10 −0.10 −0.16, 0.05 −0.16 −0.23, −0.01

Abbreviations: BCI, bootstrap confidence interval; RD, risk difference.

a

The authors assumed that the sensitivity functions followed linear structures, such that c(z = 1, e) = c1 + s1e and c(z = 0, e) = r × (z = 1, e).

b

The 95% bootstrap confidence intervals were obtained using the 2.5% and 97.5% percentiles among the 1,000 bootstrap replications.