Human IL-1Ra production from gene-transferred porcine hepatocytes. (a) The levels of human IL-1Ra produced from AdIL-1Ra transfected porcine hepatocytes on day 1 after transfection. *p < 0.001 vs. MOI 1, 5, 25, and 625. (b) Time course of human IL-1Ra production from porcine hepatocytes after MOI 125 transfection. The results are expressed as means ± SD. *p < 0.05 vs. day 1; IL-1Ra, interleukin-1 receptor antagonist; MOI, multiplicity of infection; AdIL-1Ra, adenoviral vector encoding human IL-1Ra gene.