Table 1.
Treg suppressive activity pre- versus post-vaccination
| Patients | Patients with OS > HPS | Patients | Patients with OS < HPS | ||||
|---|---|---|---|---|---|---|---|
| % Treg suppression | ∆ Suppression | % Treg suppression | ∆ Suppression | ||||
| Pre | Post | Post − pre | Pre | Post | Post − pre | ||
| Patients with decreased suppression | Patients with decreased suppression | ||||||
| #1 | 72.1 | 56.4 | −15.7 | #2 | 65.0 | 45.0 | −20.0 |
| #3 | 83.9 | 73.0 | −10.9 | #11 | 55.8 | 30.8 | −25.0 |
| #6 | 25.7 | 24.4 | −1.3 | ||||
| #14 | 38.7 | 29.1 | −9.6 | ||||
| #15 | 76.9 | 64.2 | −12.7 | ||||
| #17 | 23.8 | 14.1 | −9.7 | ||||
| #19 | 50.6 | 40.1 | −10.5 | ||||
| #20 | 48.3 | 23.8 | −24.5 | ||||
| #23 | 66.3 | 43.0 | −23.3 | ||||
| #24 | 93.3 | 85.0 | −8.3 | ||||
| #25 | 52.9 | 22.3 | −30.6 | ||||
| #32 | 33.5 | 15.1 | −18.4 | ||||
| Mean | 55.5 | 40.9 | −14.6 | Mean | 60.4 | 37.9 | −22.5 |
| Patients with increased suppression | Patients with increased suppression | ||||||
| #5 | 37.8 | 55.3 | 17.5 | #4 | 37.0 | 55.3 | 18.3 |
| #13 | 39.0 | 59.0 | 20.0 | #8 | 40.2 | 63.0 | 22.8 |
| #26 | 63.3 | 90.6 | 27.3 | #12 | 28.4 | 39.3 | 10.9 |
| #18 | 51.7 | 64.6 | 12.9 | ||||
| #21 | 50.4 | 74.3 | 23.9 | ||||
| #28 | 61.9 | 75.0 | 13.1 | ||||
| Mean | 46.7 | 68.3 | 21.6 | Mean | 44.9 | 61.9 | 17.0 |
Results are expressed as % of Treg suppression of CD4+CD25− effector cell proliferation