Table 2.
β-Lactamases and ESBLs families.
| Amber class A β-lactamases and ESBLs | Number of variants* | Amber class B β-lactamases and MBLs | Number of variants* | Amber class C β-lactamases and ESBLs | Number of variants* | Amber class D β-lactamases and ESBLs | Number of variants* |
|---|---|---|---|---|---|---|---|
| blaACI | 1 | blaB | 13 | blaACCa | 4 | ampH | 1 |
| blaAER | 1 | blaCGB | 2 | blaACTa | 9 | ampS | 1 |
| blaAST | 1 | blaDIM | 1 | blaBIL | 1 | blaLCR | 1 |
| blaBEL | 3 | blaEBR | 1 | blaBUT | 2 | blaNPS | 1 |
| blaBES | 1 | blaGIM | 1 | blaCFEa | 1 | blaOXAa | 219 |
| blaBIC | 1 | blaGOB | 18 | blaCMG | 1 | loxA | 1 |
| blaBPS | 5 | blaIMPa | 30 | blaCMYa | 72 | ||
| blaCARB | 8 | blaINDa | 7 | blaDHAa | 8 | ||
| blaCKO | 5 | blaJOHN | 1 | blaFOXa | 10 | ||
| blaCME | 2 | blaMUS | 1 | blaLATa | 1 | ||
| blaCTX-Ma | 119 | blaNDM | 6 | blaLENc | 24 | ||
| blaDES | 1 | blaSPM | 1 | blaMIRa | 5 | ||
| blaERP | 1 | blaTUS | 1 | blaMOR | 1 | ||
| blaFAR | 2 | blaVIMa | 30 | blaMOXa | 8 | ||
| blaFONA | 6 | cepA | 7 | blaOCH | 7 | ||
| blaGESa,b | 17 | cfiA | 16 | blaOKP-Ac | 16 | ||
| blaHERA | 8 | cphA | 8 | blaOKP-Bc | 20 | ||
| blaIMI | 3 | imiH | 1 | blaOXYc | 23 | ||
| blaKLUAd | 12 | imiS | 1 | blaTRU | 1 | ||
| blaKLUCd | 2 | blaZEG | 1 | ||||
| blaKLUG | 1 | cepH | 1 | ||||
| blaKLUY | 4 | ||||||
| blaKPCa | 11 | ||||||
| blaLUT | 6 | ||||||
| blaMAL | 2 | ||||||
| blaMOR | 1 | ||||||
| blaNMC-A | 1 | ||||||
| blaPERa | 7 | ||||||
| blaPME | 1 | ||||||
| blaPSE | 4 | ||||||
| blaRAHN | 2 | ||||||
| blaROB | 1 | ||||||
| blaSED | 1 | ||||||
| blaSFC | 1 | ||||||
| blaSFO | 1 | ||||||
| blaSHVa | 141 | ||||||
| blaSMEa | 3 | ||||||
| blaTEMa | 187 | ||||||
| blaTLA | 1 | ||||||
| blaTOHO | 1 | ||||||
| blaVEBa | 7 | ||||||
| blaZ | 1 | ||||||
| cdiA | 1 | ||||||
| cfxA | 6 | ||||||
| cumA | 1 | ||||||
| hugA | 1 | ||||||
| penA | 1 |
*Last update: June 17th, 2011.
aAccording to http://www.lahey.org/Studies.
bGES and IBC-type ESBLs have all been renamed as blaGES according to Weldhagen et al. (2006).
cAccording to http://www.pasteur.fr/ip/easysite/go/03b-00002u-03q/beta-lactamase-enzyme-variants.
dblaKLUA, blaKLUC, blaKLUG, and blaKLUY seem to be the chromosomal progenitors of acquired CTX-M group 2, 1, 8, and 9 genes, respectively (Saladin et al., 2002; Olson et al., 2005).