Table 3.
Acquired chloramphenicol resistance genes.
| Group | Gene | Gene(s) included | Mechanism | Length (nt) | Accession number | Coding region | Genera |
|---|---|---|---|---|---|---|---|
| Type A-1 | catA1 | cat, catI, pp-cat | Inactivating enzyme | 660 | V00622 | 244..903 | Acinetobacter, Escherichia, Klebsiella, Salmonella, Serratia, Shigella |
| Type A-2 | catA2 | cat, catII | Inactivating enzyme | 642 | X53796 | 187..828 | Aeromonas, Agrobacterium, Escherichia, Haemophilus, Photobacterium, Salmonella |
| Type A-3 | catA3 | cat, catIII | Inactivating enzyme | 642 | X07848 | 272..913 | Actinobacillus, Edwardsiella, Klebsiella, Mannheimia, Pasteurella, Shigella |
| Type A-4 | Cat | Inactivating enzyme | 654 | M11587 | 880..1533 | Proteus | |
| Type A-5 | Cat | Inactivating enzyme | 663 | P20074* | 1002758..1003420 | Streptomyces | |
| Type A-6 | cat86 | Inactivating enzyme | 663 | K00544 | 145..807 | Bacillus | |
| Type A-7 | cat(pC221) | cat, catC | Inactivating enzyme | 648 | X02529 | 2267..2914 | Bacillus, Enterococcus, Lactobacillus, Staphylococcus, Streptococcus |
| Type A-8 | cat(pC223) | cat | Inactivating enzyme | 648 | AY355285 | 1000..1647 | Enterococcus, Lactococcus, Listeria, Staphylococcus, Streptococcus |
| Type A-9 | cat(pC194) | cat, cat-TC | Inactivating enzyme | 651 | NC_002013 | 1260..1910 | Bacillus, Enterococcus, Lactobacillus, Staphylococcus, Streptococcus |
| Type A-10 | Cat | Inactivating enzyme | 687 | AY238971 | 1055..1741 | Bacillus | |
| Type A-11 | catP | catD | Inactivating enzyme | 624 | U15027 | 2953..3576 | Clostridium, Neisseria |
| Type A-12 | catS | Inactivating enzyme | 492§ | X74948 | 1..492 | Streptococcus | |
| Type A-13 | Cat | Inactivating enzyme | 624 | M35190 | 309..932 | Aeromonas, Campylobacter | |
| Type A-14 | Cat | Inactivating enzyme | 651 | S48276 | 479..1129 | Listonella, Photobacterium, Proteus | |
| Type A-15 | catB | Inactivating enzyme | 660 | M93113 | 145..804 | Clostridium | |
| Type A-16 | catQ | Inactivating enzyme | 660 | M55620 | 459..1118 | Clostridium, Streptococcus | |
| Type B-1 | catB1 | cat | Inactivating enzyme | 630 | M58472 | 148..777 | Agrobacterium |
| Type B-2 | catB2 | Inactivating enzyme | 633 | AF047479 | 5957..6589 | Acinetobacter, Aeromonas, Bordetella, Escherichia, Klebsiella, Pasteurella, Pseudomonas, Salmonella | |
| Type B-3 | catB3 | catB4, catB5, catB6, catB8 | Inactivating enzyme | 633 | AJ009818 | 883..1515 | Acinetobacter, Aeromonas, Bordetella, Enterobacter, Escherichia, Klebsiella, Kluyvera, Morganella, Pseudomonas, Salmonella, Serratia, Shigella |
| Type B-4 | catB7 | Inactivating enzyme | 639 | AF036933 | 177..815 | Pseudomonas | |
| Type B-5 | catB9 | Inactivating enzyme | 630 | AF462019 | 27..656 | Vibrio | |
| Type B-6 | catB10 | Inactivating enzyme | 633 | AF878850 | 1197..1829 | Pseudomonas | |
| Type E-1 | cmlA1 | cmlA, cmlA2, cmlA4, cmlA5, cmlA6, cmlA7, cmlA8, cmlA10, cmlB | Efflux | 1,260 | M64556 | 601..1860 | Acinetobacter, Aeromonas, Arcanobacterium, Enterobacter, Escherichia, Klebsiella, Pseudomonas, Salmonella, Serratia, Staphylococcus |
| Type E-2 | cml | Efflux | 903 | M22614 | 427..1335 | Escherichia | |
| Type E-3 | floR | cmlA-like, flo, pp-flo, cmlA9 | Efflux | 1,215 | AF071555 | 4445..5659 | Acinetobacter, Aeromonas, Bordetella, Pasteurella, Salmonella, Stenotrophomonas, Vibrio |
| Type E-4 | fexA | Efflux | 1,428 | AJ549214 | 177..1604 | Bacillus, Staphylococcus | |
| Type E-5 | cml | Efflux | 1,179 | X59968 | 508..1686 | Corynebacterium, Pseudomonas | |
| Type E-6 | cmlv | Efflux | 1,311 | U09991 | 28..1338 | Staphylococcus | |
| Type E-7 | cmrA | cmr | Efflux | 1,176 | Z12001 | 993..2168 | Uncultured |
| Type E-8 | cmr | cmx | Efflux | 1,176 | U85507 | 3518..4693 | Acinetobacter, Escherichia, Klebsiella, Salmonella, Serratia, Shigella |
| cfr | Inactivating enzyme | 1,050 | AJ579365 | 6290..7339 | Aeromonas, Agrobacterium, Escherichia, Haemophilus, Photobacterium, Salmonella | ||
| pexA | Efflux | 1,248 | HM537013 | 24055..25302 | Actinobacillus, Edwardsiella, Klebsiella, Mannheimia, Pasteurella, Shigella |