Table 7.
Acquired trimethoprim resistance genes.
| Gene | Sub-family | Gene(s) included | Length (nt) | Accession number | Coding region | Genera |
|---|---|---|---|---|---|---|
| dfrA1 | dfrA1-group | dhfrIb, dfr1, dhfrI | 474 | X00926 | 236..709 | Actinobacter, Enterobacter, Escherichia, Klebsiella, Morganella, Proteus, Pseudomonas, Salmonella, Serratia, Shigella, Vibrio |
| dfrA3 | 489 | J03306 | 103..591 | Salmonella | ||
| dfrA5 | dfrA1-group | dhfrV, dfrV | 474 | X12868 | 1306..1779 | Aeromonas, Enterobacter, Escherichia, Klebsiella, Salmonella, Vibrio |
| dfrA6 | dfrA1-group | dfrVI | 474 | Z86002 | 336..809 | Escherichia, Proteus, Vibrio |
| dfrA7 | dfrA1-group | dhfrVII, dfrVII, dfrA17 | 474 | X58425 | 594..1067 | Actinobacter, Escherichia, Proteus, Salmonella, Shigella |
| dfrA8 | 510 | U10186 | 711..1220 | Shigella | ||
| dfrA9 | 534 | X57730 | 726..1259 | Escherichia | ||
| dfrA10 | 564 | L06418 | 5494..6057 | Actinobacter, Escherichia, Klebsiella, Salmonella | ||
| dfrA12 | dfrA12-group | dhfrXII, dfr12 | 498 | Z21672 | 310..807 | Actinobacter, Aeromonas, Enterobacter, Enterococcus, Citrobacter, Klebsiella, Pseudomonas, Serratia, Salmonella, Staphylococcus |
| dfrA13 | dfrA12-group | 498 | Z50802 | 718..1215 | Escherichia | |
| dfrA14 | dfrA1-group | dhfrIb | 474 | Z50805 | 72..545 | Achromobacter, Aeromonas, Escherichia, Klebsiella, Salmonella, Vibrio |
| dfrA15 | dfrA1-group | dhfrXVb | 474 | Z83311 | 357..830 | Enterobacter, Klebsiella, Morganella, Proteus, Pseudomonas, Salmonella, Vibrio |
| dfrA16 | dfrA1-group | dhfrXVI, dfr16 | 474 | AF077008 | 115..588 | Aeromonas, Escherichia, Salmonella |
| dfrA17 | dfrA1-group | dhfrXVII, dfr17 | 474 | AB126604 | 98..571 | Actinobacter, Enterobacter, Klebsiella, Pseudomonas, Salmonella, Serratia, Shigella, Staphylococcus |
| dfrA18 | dfrA19 | 570 | AJ310778 | 7004..7573 | Enterobacter, Klebsiella, Salmonella | |
| dfrA20 | 510 | AJ605332 | 1304..1813 | Pasteurella | ||
| dfrA21 | dfrA12-group | dfrxiii | 498 | AY552589 | 1..498 | Klebsiella, Salmonella |
| dfrA22 | dfrA12-group | dfr22, dfr23 | 498 | AJ628423 | 325..822 | Escherichia, Klebsiella |
| dfrA23 | 561 | AJ746361 | 6743..7303 | Salmonella | ||
| dfrA24 | 558 | AJ972619 | 83..640 | Escherichia | ||
| dfrA25 | dfrA1-group | 459 | DQ267940 | 54..512 | Citrobacter, Salmonella | |
| dfrA26 | 552 | AM403715 | 303..854 | Escherichia | ||
| dfrA27 | dfrA1-group | dfr | 474 | EU675686 | 2543..3016 | Escherichia |
| dfrA28 | dfrA1-group | 474 | FM877476 | 116..589 | Aeromonas | |
| dfrA29 | dfrVII, dfrA7 | 472 | AM237806 | 615..1086 | Salmonella | |
| dfrA30 | dhfrV | 474 | AM997279 | 705..1178 | unknown | |
| dfrA31 | dfr6 | 474 | AB200915 | 1832..2305 | Vibrio | |
| dfrA32 | dfrA1-group | 474 | GU067642 | 535..1008 | Laribacter, Salmonella | |
| dfrA33 | dfrA12-group | 498 | FM957884 | 88..585 | Unknown | |
| dfrB1 | dhfrIIa, dfr2a | 237 | U36276 | 717..953 | Aeromonas, Bordetella, Escherichia, Klebsiella | |
| dfrB2 | dhfrIIb, dfr2b | 237 | J01773 | 809..1045 | Escherichia | |
| dfrB3 | dhfrIIc, dfr2c | 237 | X72585 | 5957..6193 | Aeromonas, Enterobacter, Escherichia, Klebsiella | |
| dfrB4 | dfr2d | 237 | AJ429132 | 69..305 | Aeromonas, Escherichia, Klebsiella | |
| dfrB5 | dfr2e | 237 | AY943084 | 2856..3092 | Pseudomonas | |
| dfrB6 | 237 | DQ274503 | 394..630 | Salmonella | ||
| dfrB7 | 237 | DQ993182 | 244..480 | Aeromonas | ||
| dfrB8 | 249 | GU295656 | 1048..1296 | Aeromonas | ||
| dfrC | dfrA | 486 | Z48233 | 337..822 | Staphylococcus | |
| dfrD | 489 | Z50141 | 94..582 | Listeria, Staphylococcus | ||
| dfrG | 498 | AB205645 | 1013..1510 | Enterococcus, Staphylococcus | ||
| dfrK | 492 | FM207105 | 2788..3279 | Staphylococcus |