Table 4.

Annual CT screening vs. no intervention. Sensitivity analyses in cohorts of men age 50.

Scenario	$/QALY compared to no intervention
Base Case*	$149,000
70% Adherence to screening	$180,000
CT sensitivity = 100%	$141,000
Less-costly helical CT ($188, HOPPS)	$120,000
Follow up nodules <4mm	$148,000
Lower operative mortality (3%, lobectomy; 0.1% mediastinoscopy; 0.2% VATS)	$141,000
Delay before return to baseline health after resection:
1 month	$147,000
6 months	$150,000
12 months	$154,000
24 months	$161,000
No recovery	$209,000

^*Base case values: perfect adherence; CT sensitivity based on diameter; screening CT cost of $283 based on Physician Fee Schedule; no follow-up of nodules <4mm; operative mortality 4% (lobectomy), 0.3% (mediastinoscopy) and 0.5% (VATS); and 3 month recovery after resection. HOPPS, Hospital Outpatient Prospective Payment System; VATS, video-assisted thoracoscopy.