Table 1.

Univariate Analysis of the Association of Patient Characteristics and Poor Treatment Outcomes, Defined as Treatment Failure or Death

Characteristica	Poor outcome with characteristic	Poor outcome without characteristic	Odds ratio	Pb
KatG 315 mutation (vs other mutations)	9/31	11/40	1.1	.88
HIV positive	5/26	19/82	0.79	.79c
Age in tertiles
44–67 years	5/48	20/78	1.0	…
33–43 years	11/37	14/89	3.6	.07
11–32 years	9/41	16/85	2.4	.62
Weight <50 kg	15/67	7/26	1.2	.73
Female sex	10/50	15/76	1.0	.97
Black African (vs Cape Coloured)	2/15	23/111	0.59	.73c
New (vs retreatment)	3/28	21/95	0.42	.28c
Beijing strain	8/23	10/36	1.4	.57
Streptomycin	17/93	8/33	0.7	.46
High-dose isoniazid	15/88	10/38	0.58	.23
Initial smear results positive (vs negative)	21/79	3/46	5.2	.009c

NOTE. Data are proportion of patients unless otherwise specified. HIV, human immunodeficiency virus.

^aPatients were included in the analysis if they had a final treatment outcome recorded and a characteristic of interest recorded. The 29 patients who defaulted or transferred out were also considered missing.

^bχ² test, except where otherwise indicated.

^cFisher exact test.