TABLE 3.

Arterial plasma C-peptide, glucagon, and cortisol levels before treatment (0 min) and during the experimental period (65–485 min)

Mean ± S.E.M.; n = 9 per group.

	0	65	125	185	245	305	365	425	485
Arterial plasma C-peptide (ng/ml)
Inhalation	0.21 ± 0.03	0.02 ± 0.01	0.02 ± 0.01	0.03 ± 0.01	0.03 ± 0.01	0.02 ± 0.01	0.03 ± 0.01	0.06 ± 0.03	0.06 ± 0.04
Intravenous infusion	0.26 ± 0.07	0.04 ± 0.02	0.04 ± 0.01	0.05 ± 0.02	0.05 ± 0.02	0.04 ± 0.01	0.04 ± 0.02	0.05 ± 0.02	0.08 ± 0.04
Arterial plasma glucagon (pg/ml)
Inhalation	39 ± 4	37 ± 3	35 ± 2	35 ± 1	37 ± 2	36 ± 2	33 ± 2	33 ± 2	29 ± 2
Intravenous infusion	42 ± 3	51 ± 2	41 ± 3	37 ± 5	41 ± 3	38 ± 2	38 ± 3	33 ± 3	37 ± 3
Arterial plasma cortisol (μg/ml)
Inhalation	5.5 ± 0.9	6.7 ± 1.7	5.1 ± 1.4	3.4 ± 0.4	2.4 ± 0.2	2.5 ± 0.5	3.5 ± 0.5	3.9 ± 1.0	3.6 ± 0.4
Intravenous infusion	10.7 ± 1.9	7.8 ± 1.1	4.0 ± 0.6	3.9 ± 0.6	3.1 ± 0.5	3.3 ± 0.5	4.0 ± 0.9	3.5 ± 0.6	5.4 ± 1.1