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. Author manuscript; available in PMC: 2011 Oct 26.
Published in final edited form as: Hypertension. 2008 May 19;52(1):150–155. doi: 10.1161/HYPERTENSIONAHA.107.104158

Figure 4.

Figure 4

Ang II-induced relaxations of isolated bovine adrenal cortical arteries. A. Effect of the NO synthase inhibitor, L-NA (30 μmol/L) and the AT1 receptor antagonist, losartan (1 μmol/L). Relaxations were performed under control conditions or after treatment with losartan or L-NA. B. Effect of L-NA on losartan-enhanced Ang II relaxations. Relaxations were performed on losartan-treated arteries before and after treatment with L-NA. C. Effect of the Ang (1-7) receptor antagonist, Ala7-Ang (1-7) (1 μmol/L) on losartan-enhanced Ang II relaxations. Relaxations were performed on losartan-treated arteries before and after treatment with Ala7-Ang (1-7). D. Effect of the AT2 receptor antagonist, PD123319 (1 and 10 μmol/L) on losartan-enhanced Ang II relaxations. Relaxations were performed on losartan-treated arteries before and after treatment with PD123319. n = 5–34, * p< 0.05 vs. control or losartan.