Ang (1-7)-induced relaxations of isolated bovine adrenal cortical arteries. A. Effect of the NO synthase inhibitor, L-NA (30 μmol/L) and endothelium removal. Responses to Ang (1-7) were performed before and after treatment with L-NA or after endothelial cell removal. B. Effect of the Ang (1-7) receptor antagonist, Ala7-Ang (1-7) (1 μmol/L), the AT1 receptor antagonist, losaratan (1 μmol/L) or the AT2 receptor antagonist, PD123319 (10 μmol/L). Responses were performed before and after receptor antagonist treatment. n = 6–21. * p< 0.05 vs. control.