Fig. 9.

Homologous competition of radiotracer and nonradioactive JHW 007 in the presence of a saturating concentration of WIN 35428 in the presence (▴) or absence (▪) of triprolidine. The curves represent the results of a single experiment with vertical bars representing S.E.M. from three tubes. The results were selected from at least three as representative of the binding parameters resulting from a global modeling of all of the replications. The concentrations of WIN 35428 (5.6 μM) and triprolidine (28 μM) added to the tubes were selected to saturate those sites.