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. 2010 Dec;335(3):703–714. doi: 10.1124/jpet.110.171629

TABLE 3.

Affinities of JHW 007 in displacement of indicated radioligands for M1 and H1 receptors.

Target Ligand WT Ki Value with 95% Confidence Limits DAT KO Ki Value with 95% Confidence Limits Ki Value at Target in Rat Brain with S.E.M.
nM
Muscarinic M1 [3H]Pirenzepine 388 (272–554) 364 (296 to 448) 399 ± 28.3a
Histamine H1 [3H]Mepyramine 24.2 (19.2–30.5) 27.9 (21.7 to 36.0) 24.6 ± 2.43
a

Value from Katz, et al. (2004).