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. 2011 Oct 26;6(10):e26634. doi: 10.1371/journal.pone.0026634

Figure 3. Functional GO categories in which celastrol-regulated proteins are relatively overrepresented.

Figure 3

(A) The distribution frequencies for up-regulated proteins (red bars) into GO categories compared to the corresponding frequencies of the entire collection of proteins quantified in the cellular proteome study (gray bars). Only Go categories in which a Pearson Chi-Square statistical test indicates a significant overrepresentation of the up-regulated proteins are displayed. (B) Distribution of down-regulated proteins (green bars) into GO categories, analyzed as described in (A).