Table 1. Overview of proteins quantified in cellular and mitochondrial proteome approaches.

	Identified Proteins*	Proteins with quantitative data¤	Core proteins	Mitocarta proteins≠	Core mitocarta proteins	Proteins changed at least 1.5-fold#
Cellular proteome	3342	2765	1779	482	314	158
Mitochondrial proteome	2404	1822	1083	498	375	33

*Excluding proteins judged as contaminants or identified in the reversed decoy database.

^¤A quantitative SILAC protein ratio (treated/untreated) was calculated from at least two valid peptide ratio counts.

^≠Based on reference to human Mitocarta, a compendium of genes encoding proteins with solid evidence of mitochondrial origin.

^#Inclusion criteria: t-test for mean ratio different from 1 (p<0.05), and mean ratio ≥1.5 or mean ratio ≤0.67.