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. 2011 Oct 26;6(10):e26776. doi: 10.1371/journal.pone.0026776

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Jayakumar et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Confluent TKPTS cells were subjected to hypoxia followed by 2 hr of reoxygenation and supernatant was then harvested. Netrin-1 was quantified by ELISA. Hypoxia and reoxygenation significantly increased netrin-1 production which was suppressed in the presence of U0126. *, p<0.001 vs. control. #, p<0.001 vs. cisplatin. n = 6.