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. 2011 Oct 26;6(10):e26981. doi: 10.1371/journal.pone.0026981

Figure 1. HCV E2 amino-acid sequence variability in HCV quasispecies derived from HCV-infected subjects.

Figure 1

A. Consensus E2 amino-acid sequences were determined in 17 HCV-infected subjects and in the HCV-1a infected serum donor from ref. 14 based on the identity of the most frequent amino-acid residue at each position. 1: R or H; 2: V or I; 3: A or T; 4: R or Q. B. Variability at each amino acid position was computed using the Entropy-ONE Web tool [58]. C. Amino-acid segments that were shown to be important for binding of the AR3B antibody [14].