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. Author manuscript; available in PMC: 2011 Oct 27.
Published in final edited form as: Cancer Res. 2010 May 1;70(9):3687–3696. doi: 10.1158/0008-5472.CAN-09-3931

Figure 6.

Figure 6

Biodegradation of S1MP. The mice (n = 5) were injected with S1MP-Alexa555-siRNA-DOPC and the liver and spleen were harvested at indicated time points. The organs were processed for silicon contents analysis and SEM images. A and B, inductively coupled plasma analysis was performed to determine the silicon contents in the liver and spleen at different time points. Silicon (Si) amounts were expressed as % of injected dose per organs (% ID). C, the S1MPs were isolated from the liver and spleen homogenates and further cleaned by sonication for SEM analysis. SEM images show time-dependent biodegradation of S1MP in the liver and spleen at day 7 and 15. Original magnification, ×50,000).