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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biomaterials. 2011 Jun 8;32(26):6183–6193. doi: 10.1016/j.biomaterials.2011.04.036

Fig. 6.

Fig. 6

(A) The bone mineral density (BMD) of ectopic bone formed by the rhBMP-2/rhVEGF165 combination scaffolds is 28 ± 4.59% and 32 ± 2.73% higher than bone formed by rhBMP-2 scaffold at 4 and 9 weeks respectively at the periphery of the scaffolds. (B) In the interior, the BMD for the combination growth factor scaffolds is higher than the single rhBMP-2 scaffolds indicating that more bone is present in the interior, which matures from 4 to 9 weeks as indicated by the increase in BMD. (C) The trabecular thickness of the bone formed is an important measure of bone maturation, and the trabecular thickness of the bone formed by the combination scaffolds is about 3 times and 4.5 times that of bone formed by rhBMP-2 scaffolds at 4 and 9 weeks. (s.d., n=9, ** p < 0.01; ns = not significant; all others p < 0.001)