Table 2.
Specific activity values for P4-P3’ factor VIII mutants
| Factor VIII | Specific Activity |
|---|---|
| % | |
| WT | 100 ± 26 |
| Pro333Val | 64 ± 2.5 |
| Gln334Asp | 117 ± 3.8 |
| Leu335Gln | 120 ± 25 |
| Leu335Arg | 117 ± 20 |
| Met337Gly | 119 ± 4.0 |
| Lys338Ile | 135 ± 22 |
| Lys338Asn | 121 ± 21 |
| Asn339Gln | 84 ± 9.4 |
Specific activity values are shown as a percentage ± standard deviation of wild type, as described under Materials and Methods. Values are determined from at least three separate determinations.