SRCs coactivate nuclear receptors (NRs), as well as numerous transcription factors. Once tethered to chromatin via these interactions, SRCs recruit a number of secondary coactivators that interact with its activation domains (ADs). This is a representative list of just some of SRC s interacting proteins, of which SRC-interacting domains have been mapped. Proteins are referenced and adapted from (Kim, 2008) (Yan J., 2008) (Xu et al., 2009) and as mentioned throughout the text.