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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Gastroenterology. 2011 Jul 27;141(5):1915–1926.e14. doi: 10.1053/j.gastro.2011.07.033

Figure 5. Time course of pancreatic injury.

Figure 5

(A) Mice were depleted of DC and treated with various doses of caerulein over 1-2 days. Mice were sacrificed either one hour after the final dose or after a 12 hour delay and pancreata examined by H&E staining (average of 3 mice per data point). (B) Mice were treated with 1, 3, 7, or 14 doses of caerulein and sacrificed either one hour or 12 hours after the final treatment. Formalin-fixed, paraffin-embedded pancreata were then examined by TUNEL staining (*p<0.05; **p<0.01; ***p<0.001).