Table III.

Efficacy, dose change requirements, and side effects of BTX injections.

	Group 1	Group 2	p- value
Efficacy
Effective injections	204 (93%)	180 (94%)	0.6895
Ineffective injections	15 (7%)	11 (6%)
Breathiness
No breathiness	170 (78%)	137 (71%)	0.1732
Breathiness	49 (22%)	54 (29%)
Dysphagia
No dysphagia	217 (99%)	191 (99%)
Dysphagia	2 (1%)	2 (1%)
Dose change
Injection dose unchanged	117 (60%)	95 (59%)	0.8367
Injection dose changed	78 (40%)	65 (41%)

Group 1 = point-touch technique; Group 2 = EMG guided technique.

There were no statistical differences noted between groups and rate of effective injection, need to change dose, or breathiness. (all p>0.05). There was no difference between groups and the rate of dysphagia, though this was not statistically analyzed as there were too few events. The dose effect, presence of breathiness, and presence of dysphagia were not described in the hospital charts of 7, 7, and 5 subjects, respectively. These few were pair-wise dropped and the total number statistically analyzed are reflected in the table.

Total subjects in each subgroup have different totals (n) reflecting analysis of quantifiable data for the statistical model. For instance, even though 417 injections were available for analysis, only 355 (195 injections and 160 injections, Groups 1 & 2 respectively) were analyzed for dose change, as the final injection for each subject was not included because a subsequent dose change could not be determined.