Figure 8.

Gentamicin immunoelectron microscopy. A. Immunogold labeling (►) for gentamicin is also strongly associated with the nucleus of mature hair cells; inset (=outlined area in main panel) shows strong labeling within the center of the nucleus. B. Antigentamicin immunogold labeling sections cut from an explant not incubated withgentamicin reveals some nonspecific labeling within the nucleus. Inset shows little nonspecific gold labeling within the center of the nucleus. C. Immunogold labeling for gentamicin is also associated with the nucleus of immature hair cells (IM), with a comparative lack of labeling in adjacent supporting cell nucleus (SC). Inset shows strong gold labeling within the center of the immature hair cell nucleus compared with the supporting cell nucleus. Scale bars in µm.