Table 1.
Urinalysis data (±SD) for 18 h collections from rats at intervals after gavage dosing of 6.25 mg OTA. Units; volume (mL), creatinine (mmol/L), and other parameters (mmol/mmol creatinine).
| Volumes | Creatinine | Calcium | Urate | Protein | Na | K | PO4 | Urea | |
|---|---|---|---|---|---|---|---|---|---|
| Pre-OTA | 7.5 (2.60) | 10.63 (2.65) | 0.31 (0.02) | 0.12 (0.04) | 0.40 (0.16) | 7.54 (3.18) | 19.45 (4.62) | 2.28 (0.77) | 87.39 (6.79) |
| 8–25 h | 7.17 (1.04) | 9.18 (0.98) | 0.33 (0.09) | 0.2 (0.05) | 0.39 (0.16) | 12.32 (4.77) | 12.83 (2.03) | 3.55 (1.40) | 77.27 (0.67) |
| 55–74 h | 15.8 (10.37) | 6.50 (3.94) | 0.18 (0.11) | 0.2 (0.15) | 0.42 (0.12) | 11.67 (2.24) | 12.66 (0.82) | 5.56 (0.68) | 60.14 (2.02) |
| 79–88 h | 30.7 (2.87) | 2.29 (0.13) | 0.13 (0.09) | 0.1 (0.02) | 0.63 (0.07) | 7.03 (1.79) | 18.76 (2.05) | 4.41 (1.02) | 58.00 (1.82) |
| 6 months | 7.97 (1.56) | 10.55 (1.96) | 0.27 (0.11) | 0.17 (0.02) | 0.37 (0.23) | 3.39 (1.20) | 14.93 (1.46) | 2.64 (0.40) | 61.44 (1.64) |
| 12 months | 14.5 | 4.66 | 1.28 | 0.34 | 3.04 | 10.33 | 22.27 | 6.19 | 52.56 |