Table 2.
Matched groups of MHD patients and their demographic, clinical and laboratory values
| Variables | AA (n = 59) | HW (n = 59) | NHW (n = 59) | p value AA vs. NHW | p value HW vs. NHW |
|---|---|---|---|---|---|
| Age, years (matched ± 5 years) | 58±16 | 58±17 | 59±17 | 0.98 | 0.84 |
| Women, % (matched) | 49 | 49 | 49 | 0.99 | 0.99 |
| Diabetes mellitus, % (matched) | 56 | 56 | 56 | 0.99 | 0.99 |
| Primary insurance, % Medicare | 57 | 49 | 38 | 0.11 | 0.38 |
| Marital status, % married | 41 | 48 | 47 | 0.58 | 0.98 |
| Charlson comorbidity index score | 2.4±1.8 | 1.7±1.4 | 2.0±1.6 | 0.12 | 0.10 |
| Body composition | |||||
| BMI | 29.1±7.6 | 25.8±4.6 | 27.0±6.4 | 0.04 | 0.28 |
| Triceps skinfold, mm | 19.3±12.6 | 16.6±9.5 | 18.2±9.9 | 0.33 | 0.37 |
| Biceps skinfold, mm | 12.1±9.2 | 10.4±10.7 | 10.4±6.7 | 0.12 | 0.99 |
| MAMC, cm | 33.4±5.8 | 29.7±5.8 | 31.9±5.8 | 0.04 | 0.04 |
| NIR measured body fat, % | 26.9±12.4 | 27.1±10.0 | 28.8±10.8 | 0.57 | 0.14 |
| NIR lean body mass, kg | 59.8±11.0 | 48.8±9.1 | 53.1±12.0 | <0.01 | 0.01 |
| Hemodialysis treatment | |||||
| Dialysis vintage, months | 30±27 | 21±20 | 18±18 | <0.01 | 0.19 |
| Dialysis dose, Kt/V single pool | 1.48±0.27 | 1.70±0.36 | 1.56±0.32 | 0.27 | 0.03 |
| Erythropoietin dose, 103 U/week | 19,380±2,357 | 15,476±2,288 | 14,598±1,929 | 0.12 | 0.82 |
| Biochemical measurements | |||||
| Serum albumin, mg/dl | 3.8±0.4 | 3.8±0.4 | 3.8±0.4 | 0.79 | 0.61 |
| Prealbumin, mg/dl | 29.0±9.5 | 25.1±8.4 | 24.7±8.1 | <0.01 | 0.90 |
| Total homocysteine, μmol/l | 28.0±12.3 | 23.0±14.5 | 20.8±6.5 | <0.01 | 0.32 |
| Creatinine, mg/dl | 11.1±2.9 | 9.0±2.7 | 8.9±3.2 | <0.01 | 0.62 |
| Calcium, mg/dl | 9.5±0.6 | 9.3±0.7 | 9.2±0.5 | 0.06 | 0.56 |
| Phosphorus, mg/dl | 5.9±1.5 | 5.6±1.3 | 6.0±1.7 | 0.96 | 0.94 |
| Bicarbonate, mg/dl | 22.4±3.5 | 22.3±0.3 | 21.6±2.4 | 0.22 | 0.20 |
| TIBC, mg/dl | 207±40 | 210±45 | 225±45 | 0.06 | 0.09 |
| Iron, mg/dl | 62±27 | 68±27 | 66±32 | 0.58 | 0.87 |
| CRP, mg/1 | 6.7±6.4 | 5.6±5.9 | 7.8±8.3 | 0.47 | 0.21 |
| IL-6, pg/ml | 10.3±9.7 | 11.6±9.6 | 13.4±15.1 | 0.52 | 0.83 |
| TNF-α, pg/ml | 7.5±7.7 | 7.4±4.9 | 9.6±9.6 | 0.20 | 0.14 |
| Blood hemoglobin, g/dl | 12.2±3.1 | 12.3±3.2 | 11.9 + 2.1 | 0.31 | 0.11 |
| Lymphocyte, % | 21.1±5.7 | 17.7±7.2 | 21.6±7.7 | 0.01 | <0.01 |
For each non-Hispanic White MHD patient, an age- (± 5 years), gender- and diabetes-matched MHD patient from among African-American and Hispanic White MHD patients was selected randomly, p values are based on post hoc Bonferroni. Serum and blood values were obtained immediately predialysis except for serum urea which was obtained pre- and postdialysis. AA = African American; NHW = non-Hispanic White; HW = Hispanic White; NIR = near-infrared; TIBC = total iron-binding capacity.