Table 4.
Comparing death HR across the quartiles of the selected biochemical markers of nutritional status and inflammation in 279 African-American and 520 White (including 475 Hispanic) MHD patients in the 6-year cohort (2001-2007)
| Predialysis serum | Qi | Q2 | Q3 | Q4 | p trend |
|---|---|---|---|---|---|
| African Americans (n = 279) | |||||
| Albumin | 1 | 0.44 (0.27-0.72)∗ | 0.51 (0.32-0.83)∗ | 0.52 (0.31-0.85)∗ | 0.01 |
| Prealbumin | 1 | 0.82 (0.51-1.30) | 0.57 (0.34-0.94)∗ | 0.53 (0.31-0.91)∗ | <0.01 |
| Creatinine | 1 | 0.79 (0.48-1.29) | 0.90 (0.55-1.48) | 0.77 (0.41-1.42) | 0.50 |
| CRP | 1 | 1.71 (0.98-2.97) | 1.84 (1.05-3.21)∗ | 2.42 (1.39-4.19)∗ | <0.01 |
| IL-6 | 1 | 1.04 (0.57-1.89) | 1.53 (0.87-2.71) | 2.20 (1.28-3.79)∗ | <0.01 |
| TNF-α | 1 | 1.16 (0.69-1.94) | 0.97 (0.57-1.65) | 0.80 (0.46-1.40) | 0.30 |
| All Whites (Hispanics and non-Hispanics; n = 520) | |||||
| Albumin | 1 | 0.48 (0.33-0.69)∗ | 0.32 (0.20-0.51)∗ | 0.34 (0.19-0.58)∗ | <0.01 |
| Prealbumin | 1 | 0.56 (0.37-0.84)∗ | 0.53 (0.35-0.81)∗ | 0.55 (0.33-0.90)∗ | <0.01 |
| Creatinine | 1 | 0.79 (0.54-1.15) | 0.64 (0.42-0.99)∗ | 0.43 (0.24-0.77)∗ | <0.01 |
| CRP | 1 | 1.59 (0.95-2.67) | 2.03 (1.23-3.35)∗ | 1.87 (1.14-3.05)∗ | <0.01 |
| IL-6 | 1 | 1.88 (0.97-3.66) | 2.29 (1.20-4.37)∗ | 4.13 (2.22-7.67)∗ | <0.01 |
| TNF-α | 1 | 1.21 (0.76-1.93) | 1.37 (0.86-2.17) | 1.37 (0.86-2.18) | 0.15 |
All values are adjusted for case-mix which includes age, gender, diabetes mellitus, Charlson comorbidity index score and dialysis vintage.
∗
p < 0.05.