Table 2.
Association of individual biomarkers with subsequent preterm delivery
Biomarker | Test cutoff |
||||||||
---|---|---|---|---|---|---|---|---|---|
75th percentile |
85th percentile |
90th percentile |
|||||||
cutoff, ng/ml | OR | 95% CI | cutoff, ng/ml | OR | 95% CI | cutoff, ng/ml | OR | 95% CI | |
MIF | 9.2 | 3.5∗ | 1.8-6.7 | 10.3 | 3.3∗ | 1.6-6.9 | 12.6 | 2.8∗ | 1.2-6.5 |
TNF | 4.9 | 2.4∗ | 1.3-4.7 | 5.5 | 3.2∗ | 1.5-6.7 | 6.0 | 3.1∗ | 1.4-7.2 |
IL-6 | 3.1 | 1.5 | 0.7-2.9 | 4.1 | 2.3∗ | 1.1-5.0 | 5.7 | 2.5∗ | 1.3-4.8 |
Il-10 | 0.655 | 2.3∗ | 1.2-4.5 | 1.925 | 3.0∗ | 1.4-6.3 | 3.816 | 4.0∗ | 1.8-9.1 |
CRH bound | 62,000 | 2.4∗ | 1.2-4.6 | 124,800 | 2.7∗ | 1.3-5.7 | 189,000 | 2.3 | 1.0-5.5 |
CRH total | 63,000 | 3.2∗ | 1.7-6.2 | 140,400 | 2.7∗ | 1.3-5.7 | 227,800 | 2.1 | 0.9-5.1 |
CRP | 5,667.4 | 1.9∗ | 1.0-3.7 | 7,424.1 | 2.3∗ | 1.1-4.8 | 9,384.6 | 2.3∗ | 1.0-5.5 |
Cortisol | 1,810.0 | 1.2 | 0.6-2.3 | 2,015.6 | 2.1∗ | 1.0-4.5 | 2,369.6 | 2.3∗ | 1.0-5.5 |
Cutoffs based on control (term delivery) mothers. OR = Odds ratio; 95% CI = 95% confidence intervals.
Significant values.