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. 2010 Feb 17;70(1):40–46. doi: 10.1159/000284949

Table 2.

Association of individual biomarkers with subsequent preterm delivery

Biomarker Test cutoff








75th percentile
85th percentile
90th percentile


cutoff, ng/ml OR 95% CI cutoff, ng/ml OR 95% CI cutoff, ng/ml OR 95% CI
MIF 9.2 3.5 1.8-6.7 10.3 3.3 1.6-6.9 12.6 2.8 1.2-6.5
TNF 4.9 2.4 1.3-4.7 5.5 3.2 1.5-6.7 6.0 3.1 1.4-7.2
IL-6 3.1 1.5 0.7-2.9 4.1 2.3 1.1-5.0 5.7 2.5 1.3-4.8
Il-10 0.655 2.3 1.2-4.5 1.925 3.0 1.4-6.3 3.816 4.0 1.8-9.1
CRH bound 62,000 2.4 1.2-4.6 124,800 2.7 1.3-5.7 189,000 2.3 1.0-5.5
CRH total 63,000 3.2 1.7-6.2 140,400 2.7 1.3-5.7 227,800 2.1 0.9-5.1
CRP 5,667.4 1.9 1.0-3.7 7,424.1 2.3 1.1-4.8 9,384.6 2.3 1.0-5.5
Cortisol 1,810.0 1.2 0.6-2.3 2,015.6 2.1 1.0-4.5 2,369.6 2.3 1.0-5.5

Cutoffs based on control (term delivery) mothers. OR = Odds ratio; 95% CI = 95% confidence intervals.

Significant values.