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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Leukemia. 2011 Mar 18;25(7):1153–1158. doi: 10.1038/leu.2011.44

Figure 1. Location of mutations in the DNMT3A gene.

Figure 1

The positions and predicted translational consequences of DNMT3A mutations detected in 150 MDS samples are shown. Each circle is a mutation found in one patient. One patient has two mutations in DNMT3A. The conserved proline-tryptophan-tryptophan-proline (PWWP), zinc finger (ZNF), and methyltransferase (MTase) domains are shown.

*, stop codon.