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. 2011 Jun 20;1:6. doi: 10.1186/2191-219X-1-6

Figure 5.

Figure 5

In vivo displacement of 18F-nifene by nicotine. In vivo rat microPET brain slices of 18F-nifene before (A) and after (B) nicotine challenge. (C) Time-activity curve of 18F-nifene specific binding (thalamus-cerebellum) with nicotine (0.3 mg/kg) administered at 30 min pi, displacing 18F-nifene binding in the thalamus (inset shows dissociation rate, koff of 18F-nifene was 0.06 min-1).