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Family tree of patient FAP15. The proband is indicated by the arrow. The proband's age at onset of the polyposis (42 years) and of the rectal cancer (44 years) are indicated. The patient presented unaffected deceased parents, four unscreened (without colonoscopy) siblings and one affected sister. The affected sister presented with polyposis at the age of 44 years. The Caucasian patient stated having Portuguese great-grandparents and no report of inbreeding in her family.
