Table 3.

Adverse events reported by participants who completed all study visits

Adverse Event	Study Visits
	4-week n/n (%)	8-week n/n (%)	12-week n/n (%)	24-week n/n (%)
Throat irritation*	11/34 (32,4%)	5/32 (15,6%)	5/30 (16,7%)	4/27 (14,8%)
Mouth Irritation*	7/34 (20,6%)	4/32 (12,5%)	3/30 (10,0%)	2/27 (7,4%)
Sore Throat	4/34 (11,8%)	1/32 (3,1%)	1/30 (3,3%)	0/27 (0,0%)
Dry cough	11/34 (32,4%)	6/32 (18,8%)	3/30 (10,0%)	3/27 (11,1%)
Dry mouth	3/34 (8,8%)	1/32 (3,1%)	1/30 (3,3%)	1/27 (3,7%)
Mouth ulcers	1/34 (2,9%)	1/32 (3,1%)	1/30 (3,3%)	0/27 (0,0%)
Dizziness§	5/34 (14,7%)	2/32 (6,3%)	2/30 (6,7%)	1/27 (3,7%)
Headache	4/34 (11,8%)	2/32 (6,3%)	2/30 (6,7%)	1/27 (3,7%)
Nausea	5/34 (14,7%)	2/32 (6,3%)	1/30 (3,3%)	1/27 (3,7%)

* Throat and mouth irritation were described either as tickling, itching, or burning sensation

^§ Dizziness, was also used to mean vertigo and light-headedness.