Table 2. Analysis of 5 Diagnostic Tests used in the Evaluation of 28 Patients with Suspected Mucosal Leishmaniasis.

Assay	Number Positive	Number Negative	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
kDNA PCR of Biopsy Specimen	22	6	95.7	100.0	100.0	83.3
kDNA PCR of CerviSoft® brushes	23	10*	95.7	90.0	95.7	90.0
kDNA PCR of Histobrush® brushes	22	11*	91.3	90.0	95.5	81.8
LST	16	12	69.6	100.0	100.0	41.7
Biopsy with Histopathology	5	23	21.7	100.0	100.0	21.7

*includes nasal and buccal specimens from 5 healthy control volunteers.

Abbreviations: LST, leishmanin skin test; NPV, negative predictive value; PPV, positive predictive value.