Table 3. Enriched Pathways in Genes Differentially Expressed by v-Src and STAT3-C.
Cell process | Count | % | p-Value |
Cell adhesion - Integrin-mediated cell adhesion and migration | 19 | 42.22 | 5.56E-05 |
Cytoskeleton remodeling | 32 | 33.33 | 6.09E-05 |
Development - Angiotensin signaling via STATs | 13 | 52.00 | 6.25E-05 |
Cell adhesion, cytokine and chemokine mediated signaling pathway | 31 | 33.33 | 7.93E-05 |
Transcription - Ligand-dependent Transcription of Retinoid Target Genes | 15 | 46.88 | 8.03E-05 |
Proteolysis | 12 | 50.00 | 1.97E-04 |
Cytoskeletal remodeling and cell adhesion - Integrin outside in signaling | 18 | 39.13 | 2.79E-04 |
Development - WNT signaling, degradation of beta-catenin | 10 | 50.00 | 6.83E-04 |
G-protein signaling - RhoA regulation pathway | 14 | 41.18 | 7.26E-04 |
Immune response - IFN alpha/beta signaling pathway | 11 | 45.83 | 9.32E-04 |
Over-represented pathways identified using the MetaCore Analysis Suite (GeneGO Inc.).