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. 2011 Oct 27;6(10):e26317. doi: 10.1371/journal.pone.0026317

Figure 4. Effects of the loss of the CSF-1R on cell populations in the cortex.

Figure 4

A. 5 µm sections of cortex (a–d, g,h) and hippocampus (e, f) immunostained with anti NeuN (a, b), anti-GFAP (c–f) or anti-Nogo A antibodies (g,h). c–h counterstained with Haematoxylin. Wild Type (a,c,e,g) and Csf1r−/− mice (b,d,f,h) Bar = 20 µm. B. Total cell counts (N = 3/genotype) determined as described in the materials and methods in the regions indicated in Figure 2B 5, 6 of all Nissl stained cells (a), NeuN positive cells (b), GFAP positive cells (c) and Nogo A positive cells (d). GFAP positive cells are increased in Csf1r−/− mice compared to WT (p = 0.022) while Nogo A positive ones are decreased (p = 0.0314).