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. 2011 Oct 27;6(10):e26823. doi: 10.1371/journal.pone.0026823

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Hamtiaux et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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N-acylethanolamines AEA, PEA and OEA time- (A) and dose-dependently (B) decrease N1E-115 cell viability. Cells were seeded 5h before treatment (2000 cells/well in microwells) and incubated with increasing concentrations of N-acylethanolamines. After 24h, 48h or 72h of treatment, cytotoxicity was assessed by a MTT test. Data are expressed as percentage of the vehicle control and are the mean of three experiments performed in quintuplicate. Significantly different (**P<0.01) from vehicle incubation.