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. 2011 Oct 27;7(10):e1002314. doi: 10.1371/journal.ppat.1002314

Figure 1. Phylogenetic tree of patient 1.

Figure 1

A neighbor-joining approach, as implemented in MEGA4, was used to construct a phylogenetic tree with the best evolutionary model found in jModeltest v0.1.1. Circles and squares represent longitudinal episomal and integrated DNA sequences, respectively. Legends of phylogenetic trees represent weeks available for further analysis. Sizes of the symbols represent the different percentages of clonal sequences. 1,000 bootstrap replicates were performed; only values greater than 50% are shown at tree nodes.