Table 1.
Characteristics of 141 Aparasitemic Malian Children Aged 2–10 Years by Hemoglobin Type
| Characteristic | HbAA (n = 106) | HbAS (n = 15) | P valuea | HbAC (n = 20) | P valuea |
| Age, y (mean ± SD) | 5.7 ± 2.2 | 5.2 ± 2.2 | .51 | 6.4 ± 2.8 | .28 |
| Female sex, no. (%) | 53 (50.0) | 11 (73.3) | .11 | 9 (45.0) | .43 |
| Weight, kg (mean ± SD) | 18.0 ± 5.4 | 18.8 ± 8.2 | .95 | 19.3 ± 6.6 | .40 |
| Plasmodium falciparum smear positive at least once during the 6-mo malaria season (May–Dec), no. (%)b | 104 (98.1) | 13 (86.7) | .08 | 20 (100) | 1.00 |
Abbreviations: HbAA, hemoglobin type AA; HbAS, hemoglobin type AS; HbAC, hemoglobin type AC; SD, standard deviation.
a
The characteristics of HbAS and HbAC children were compared with those of HbAA children using Fisher exact tests and Wilcoxon rank–sum tests for binary and continuous variables, respectively.
b
P. falciparum smear positivity detected either during passive surveillance for malaria episodes over the 6-mo malaria season, or by active surveillance during 3 cross-sectional surveys conducted every 2 mo, as previously described [29].