. 2011 Oct 12;204(11):1750–1761. doi: 10.1093/infdis/jir638

Table 2.

Linear Regression Results for the Magnitude of the Immunoglobulin G Response Specific for Plasmodium falciparum Antigen Categories Before and After the Malaria Season by Hemoglobin Type, Age, and Gender

	Before malaria season (May)				After malaria season (Dec)
P. falciparum Protein Categories	Hb type (AC vs AA)	Hb type (AS vs AA)	Age	Gender	Hb type (AC vs AA)	Hb type (AS vs AA)	Age	Gender
Merozoite (RNA)	−41.9 (578.9)^a P = .9422	−140.8(659.1)^a P = .8310	567.6 (87.0)^a P < .0001	214.7 (407.0)^a P = .5987	386.9 (704.2)^a P = .5837	4.6 (661.8)^a P = .9944	426.2 (89.4)^a P < .0001	−264.6(401.9)^a P = .5114
Ring (RNA)	54.2 (444.8)^a P = .9032	−41.0(506.4)^a P = .9355	315.8 (66.8)^a P < .0001	259.1 (312.7)^a P = .4088	−6.2 (509.9)^a P = .9901	−80.7(479.2)^a P = .8665	343.2 (64.7)^a P < .0001	8.2 (291.0)^a P = .9774
Trophozoite (RNA)	50.2 (400.6)^a P = .9004	39.8 (456.2)^a P = .9305	271.0 (60.2)^a P < .0001	67.6 (281.7)^a P = .8105	194.7 (460.2)^a P = .6728	−88.7(432.5)^a P = .8377	266.2 (58.4)^a P < .0001	−102.2(262.6)^a P = .6978
Schizont (RNA)	38.7 (420.4)^a P = .9266	−51.8 (478.7)^a P = .9138	355.2 (63.2)^a P < .0001	113.7 (295.6)^a P = .7010	2.9 (500.5)^a P = .9952	−192.8(470.3)^a P = .6824	333.1 (63.6)^a P < .0001	−119.6(285.6)^a P = .6760
Gametocyte (RNA)	−72.8 (385.7)^a P = .8504	123.6 (439.2)^a P = .7787	312.4 (58.0)^a P < .0001	170.5 (271.2)^a P = .5304	−82.5 (456.7)^a P = .8567	18.3 (429.1)^a P = .9659	284.1 (58.0)^a P < .0001	−9.9(260.6)^a P = .9694
Sporozoite (protein)	31.5 (388.4)^a P = .9353	82.7 (442.2)^a P = .8518	300.4 (58.4)^a P < .0001	175.7 (273.1)^a P = .5209	19.0 (450.0)^a P = .9662	−77.7(422.8)^a P = .8545	332.1 (57.1)^a P < .0001	−24.7(256.8)^a P = .9234
Merozoite (protein)	−123.0 (443.2)^a P = .7818	−22.4 (504.6)^a P = .9645	445.4 (66.6)^a P < .0001	146.7 (311.6)^a P = .6384	−6.6 (524.4)^a P = .9899	−13.6(492.8)^a P = .9778	405.4 (66.6)^a P < .0001	−60.6(299.2)^a P = .8396
Trophozoite (protein)	65.4 (416.7)^a P = .8754	130.4 (474.5)^a P = .7838	321.3 (62.6)^a P < .0001	145.4 (293.0)^a P = .6204	211.8 (498.9)^a P = .6718	104.3 (468.8)^a P = .8242	303.3 (63.3)^a P < .0001	−55.0(284.7)^a P = .8468
Gametocyte (protein)	21.0 (383.0)^a P = .9562	134.8 (436.1)^a P = .7576	253.0 (57.6)^a P < .0001	152.4 (269.3)^a P = .5722	100.9 (447.8)^a P = .8220	−71.2(420.8)^a P = .8658	238.0 (56.9)^a P < .0001	−10.6(255.5)^a P = .9669
PEXEL or HT	−279.2 (640.6)^a P = .6635	−207.0 (729.3)^a P = .7769	586.0 (96.3)^a P < .0001	113.1 (450.4)^a P = .8020	−225.4 (837.9)^a P = .7883	27.4 (787.4)^a P = .9722	480.0 (106.4)^a P < .0001	−457.1(478.1)^a P = .3410
RBC surface expression	−54.5 (540.7)^a P = .9197	−126.1 (615.7)^a P = .8379	373.8 (81.3)^a P < .0001	164.5 (380.2)^a P = .6658	88.2 (695.5)^a P = .8992	95.9 (653.6)^a P = .8835	253.9 (88.3)^a P = .0047	−112.3(396.9)^a P = .7776
PfEMP1	−24.0 (567.2)^a P = .9663	−83.7 (645.8)^a P = .8970	410.7 (85.3)^a P < .0001	494.0 (398.8)^a P = .2175	−561.3 (816.1)^a P = .4929	−447.2(766.9)^a P = .5608	509.0 (103.7)^a P < .0001	165.1 (465.7)^a P = .7235
RIFIN	−22.9 (655.5)^a P = .9721	−642.7 (746.4)^a P = .3907	355.9 (98.5)^a P = .0004	275.7 (460.9)^a P = .5507	−222.0 (973.5)^a P = .8199	−953.4 (914.8)^a P = .2993	211.0 (123.6)^a P = .0906	45.5 (555.5)^a P = .9348
STEVOR	−58.1 (866.8)^a P = .9466	75.5 (986.9)^a P = .9390	843.6 (130.3)^a P < .0001	1240.9 (609.4)^a P = .0436	−282.8 (1364.9)^a P = .8361	−1898.7 (1282.6)^a P = .1413	1247.8 (173.4)^a P < .0001	1173.9 (778.9)^a P = .1343
SURFIN	−37.7 (295.6)^a P = .8986	−431.5 (336.6)^a P = .2020	383.8 (44.4)^a P < .0001	151.0 (207.8)^a P = .4686	−375.9 (413.0)^a P = .3645	−354.5 (388.1)^a P = .3628	399.7 (52.4)^a P < .0001	−145.2(235.7)^a P = .5390

Abbreviations: Hb, hemoglobin; PEXEL, Plasmodium export element; HT, host-targeting signal.

Regression coefficient.