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. 2011 Oct 12;204(11):1750–1761. doi: 10.1093/infdis/jir638

Table 3.

Poisson Regression Results for the Breadth of the Immunoglobulin G Response Specific for Plasmodium falciparum Antigen Categories Before and After the Malaria Season by Hemoglobin Type, Age, and Gender

Before malaria season (May)
After malaria season (Dec)
P. falciparum protein categories Hb type (AC vs AA) Hb type (AS vs AA) Age Gender Hb type (AC vs AA) Hb type (AS vs AA) Age Gender
Merozoite (RNA) 0.0281 (0.1389)a  P = .8394 −0.0495 (0.2051)a  P = .8090 0.1323 (0.0221)a  P < .0001 0.0582 (0.1096)a  P = .5952 0.0623 (0.1032)a  P = .5461 0.0518 (0.0919)a  P = .5727 0.0554 (0.0146)a  P = .0002 0.0309 (0.0677)aP = .6478
Ring (RNA) −0.0055(0.1607)a  P = .9726 −0.0282(0.2358)a  P = .9047 0.1347 (0.0263)a  P < .0001 0.0263 (0.1278)a  P = .8369 0.0617 (0.1076)a  P = .5662 0.0309 (0.1105)a  P = .7794 0.0709 (0.0169)a  P < .0001 0.0119 (0.0781)aP = .8782
Trophozoite (RNA) 0.0669 (0.1625)a  P = .6803 −0.0252(0.2198)a  P = .9086 0.1311 (0.0258)a  P < .0001 0.0603 (0.1267)a  P = .6342 0.0917 (0.1305)a  P = .4821 0.0171 (0.1128)a  P = .8791 0.0732 (0.0180)a  P < .0001 0.0375 (0.0829)aP = .6509
Schizont (RNA) 0.0159 (0.1404)a  P = .9095 0.0196 (0.1974)a  P = .9208 0.1151 (0.0246)a  P < .0001 0.0283 (0.1175)a  P = .8091 0.0391 (0.1196)a  P = .7433 0.0201 (0.1137)a  P = .8596 0.0565 (0.0172)aP = .0010 0.0360 (0.0797)aP = .6515
Gametocyte (RNA) 0.0339 (0.1731)a  P = .8445 −0.0235(0.2197)a  P = .9146 0.1283 (0.0279)a  P < .0001 0.0637 (0.1364)a  P = .6403 0.0281 (0.1378)a  P = .8383 0.0209 (0.1195)a  P = .8606 0.0690 (0.0194)aP = .0004 0.0402 (0.0914)aP = .6601
Sporozoite (protein) 0.0021 (0.1638)a  P = .9894 0.0401 (0.2228)a  P = .8568 0.1307 (0.0259)a  P < .0001 0.0381 (0.1267)a  P = .7634 0.0345 (0.1337)a  P = .7958 0.0031 (0.1219)a  P = .9795 0.0777 (0.0180)a  P < .0001 0.0231 (0.0838)aP = .7822
Merozoite (protein) −0.0001(0.1722)a  P = .9993 −0.0431(0.2481)a  P = .8618 0.1341 (0.0277)a  P < .0001 0.0641 (0.1352)a  P = .6352 0.1121 (0.1251)a  P = .3701 0.0596 (0.1167)a  P = .6090 0.0866 (0.0184)a  P < .0001 0.0630 (0.0846)aP = .4559
Trophozoite (protein) 0.0464 (0.1579)a  P = .7685 −0.0359(0.2353)a  P = .8785 0.1417 (0.0272)a  P < .0001 0.0634 (0.1320)a  P = .6307 0.0919 (0.1292)a  P = .4764 0.0911 (0.1202)a  P = .4485 0.0750 (0.0188)a  P < .0001 0.0376 (0.0857)aP = .6605
Gametocyte (protein) 0.0441 (0.1599)a  P = .7828 −0.0002(0.2016)a  P = .9988 0.1208 (0.0264)a  P < .0001 0.0336 (0.1291)a  P = .7943 0.0539 (0.1297)a  P = .6775 0.0179 (0.1171)a  P = .8780 0.0593 (0.0187)aP = .0015 0.0401 (0.0859)aP = .6399
PEXEL or HT −0.1720 (0.0969)a  P = .0761 −0.0828 (0.1756)a  P = .6371 0.1261 (0.0180)a  P < .0001 0.0566 (0.0798)a  P = .4778 0.0166 (0.0517)a  P = .7478 0.0154 (0.0493)a  P = .7543 0.0393 (0.0082)aP < .0001 0.0102 (0.0359)aP = .7756
RBC surface expression −0.0013 (0.1119)a  P = .9902 −0.0656 (0.1719)a  P = .7027 0.1055 (0.0184)aP < .0001 0.0334 (0.0873)a  P = .7014 0.0809 (0.0794)a  P = .3081 0.0098 (0.0636)a  P = .8769 0.0423 (0.0106)aP < .0001 0.0013 (0.0479)aP = .9778
PfEMP1 −0.1133 (0.0612)a  P = .0662 0.0120 (0.0696)a  P = .8629 0.0273 (0.0092)a  P = .0035 0.0375 (0.0430)a  P = .3838 1.2583 (0.8244)a  P = .1269 −0.2486 (1.1789)a  P = .8329 −0.5315 (0.2134)aP = .0127 −0.6306 (0.7596)aP = .4064
RIFIN 0.4726 (0.6521)a  P = .4686 0.0903 (0.7342)a  P = .9021 −0.2604 (0.1119)a  P = .0199 −0.5155 (0.4955)a  P = .2981 −1.2313 (4.5039)a  P = .9723 −1.5210 (5.9891)a  P = .9689 −0.2858 (0.1514)aP = .0255 −1.4801 (1.1431)aP = .1953
STEVOR 0.4189 (0.7201)a  P = .5607 1.3505 (0.7537)a  P = .0731 −0.8246 (0.1509)a  P < .0001 −0.0527 (0.4779)a  P = .9121 −0.3866 (0.9531)a  P = .6850 0.1751 (0.9150)a  P = .8482 −0.9603 (0.2290)aP < .0001 0.0006 (0.5753)aP = .9990
SURFIN −0.3894 (0.6310)a  P = .5371 −0.0056 (0.6496)a  P = .9930 −0.5354 (0.1023)a  P < .0001 −0.2299 (0.4080)a  P = .5729 −1.8858 (1.1321)a  P = .0957 −1.1453 (0.9089)a  P = .2076 −0.6083 (0.1422)aP < .0001 −0.0140 (0.4812)aP = .9766

Abbreviations: Hb, hemoglobin; PEXEL, Plasmodium export element; HT, host-targeting signal.

a

Regression coefficient.