Table 3.
Before malaria season (May) |
After malaria season (Dec) |
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P. falciparum protein categories | Hb type (AC vs AA) | Hb type (AS vs AA) | Age | Gender | Hb type (AC vs AA) | Hb type (AS vs AA) | Age | Gender |
Merozoite (RNA) | 0.0281 (0.1389)a P = .8394 | −0.0495 (0.2051)a P = .8090 | 0.1323 (0.0221)a P < .0001 | 0.0582 (0.1096)a P = .5952 | 0.0623 (0.1032)a P = .5461 | 0.0518 (0.0919)a P = .5727 | 0.0554 (0.0146)a P = .0002 | 0.0309 (0.0677)a P = .6478 |
Ring (RNA) | −0.0055(0.1607)a P = .9726 | −0.0282(0.2358)a P = .9047 | 0.1347 (0.0263)a P < .0001 | 0.0263 (0.1278)a P = .8369 | 0.0617 (0.1076)a P = .5662 | 0.0309 (0.1105)a P = .7794 | 0.0709 (0.0169)a P < .0001 | 0.0119 (0.0781)a P = .8782 |
Trophozoite (RNA) | 0.0669 (0.1625)a P = .6803 | −0.0252(0.2198)a P = .9086 | 0.1311 (0.0258)a P < .0001 | 0.0603 (0.1267)a P = .6342 | 0.0917 (0.1305)a P = .4821 | 0.0171 (0.1128)a P = .8791 | 0.0732 (0.0180)a P < .0001 | 0.0375 (0.0829)a P = .6509 |
Schizont (RNA) | 0.0159 (0.1404)a P = .9095 | 0.0196 (0.1974)a P = .9208 | 0.1151 (0.0246)a P < .0001 | 0.0283 (0.1175)a P = .8091 | 0.0391 (0.1196)a P = .7433 | 0.0201 (0.1137)a P = .8596 | 0.0565 (0.0172)a P = .0010 | 0.0360 (0.0797)a P = .6515 |
Gametocyte (RNA) | 0.0339 (0.1731)a P = .8445 | −0.0235(0.2197)a P = .9146 | 0.1283 (0.0279)a P < .0001 | 0.0637 (0.1364)a P = .6403 | 0.0281 (0.1378)a P = .8383 | 0.0209 (0.1195)a P = .8606 | 0.0690 (0.0194)a P = .0004 | 0.0402 (0.0914)a P = .6601 |
Sporozoite (protein) | 0.0021 (0.1638)a P = .9894 | 0.0401 (0.2228)a P = .8568 | 0.1307 (0.0259)a P < .0001 | 0.0381 (0.1267)a P = .7634 | 0.0345 (0.1337)a P = .7958 | 0.0031 (0.1219)a P = .9795 | 0.0777 (0.0180)a P < .0001 | 0.0231 (0.0838)a P = .7822 |
Merozoite (protein) | −0.0001(0.1722)a P = .9993 | −0.0431(0.2481)a P = .8618 | 0.1341 (0.0277)a P < .0001 | 0.0641 (0.1352)a P = .6352 | 0.1121 (0.1251)a P = .3701 | 0.0596 (0.1167)a P = .6090 | 0.0866 (0.0184)a P < .0001 | 0.0630 (0.0846)a P = .4559 |
Trophozoite (protein) | 0.0464 (0.1579)a P = .7685 | −0.0359(0.2353)a P = .8785 | 0.1417 (0.0272)a P < .0001 | 0.0634 (0.1320)a P = .6307 | 0.0919 (0.1292)a P = .4764 | 0.0911 (0.1202)a P = .4485 | 0.0750 (0.0188)a P < .0001 | 0.0376 (0.0857)a P = .6605 |
Gametocyte (protein) | 0.0441 (0.1599)a P = .7828 | −0.0002(0.2016)a P = .9988 | 0.1208 (0.0264)a P < .0001 | 0.0336 (0.1291)a P = .7943 | 0.0539 (0.1297)a P = .6775 | 0.0179 (0.1171)a P = .8780 | 0.0593 (0.0187)a P = .0015 | 0.0401 (0.0859)a P = .6399 |
PEXEL or HT | −0.1720 (0.0969)a P = .0761 | −0.0828 (0.1756)a P = .6371 | 0.1261 (0.0180)a P < .0001 | 0.0566 (0.0798)a P = .4778 | 0.0166 (0.0517)a P = .7478 | 0.0154 (0.0493)a P = .7543 | 0.0393 (0.0082)a P < .0001 | 0.0102 (0.0359)a P = .7756 |
RBC surface expression | −0.0013 (0.1119)a P = .9902 | −0.0656 (0.1719)a P = .7027 | 0.1055 (0.0184)a P < .0001 | 0.0334 (0.0873)a P = .7014 | 0.0809 (0.0794)a P = .3081 | 0.0098 (0.0636)a P = .8769 | 0.0423 (0.0106)a P < .0001 | 0.0013 (0.0479)a P = .9778 |
PfEMP1 | −0.1133 (0.0612)a P = .0662 | 0.0120 (0.0696)a P = .8629 | 0.0273 (0.0092)a P = .0035 | 0.0375 (0.0430)a P = .3838 | 1.2583 (0.8244)a P = .1269 | −0.2486 (1.1789)a P = .8329 | −0.5315 (0.2134)a P = .0127 | −0.6306 (0.7596)a P = .4064 |
RIFIN | 0.4726 (0.6521)a P = .4686 | 0.0903 (0.7342)a P = .9021 | −0.2604 (0.1119)a P = .0199 | −0.5155 (0.4955)a P = .2981 | −1.2313 (4.5039)a P = .9723 | −1.5210 (5.9891)a P = .9689 | −0.2858 (0.1514)a P = .0255 | −1.4801 (1.1431)a P = .1953 |
STEVOR | 0.4189 (0.7201)a P = .5607 | 1.3505 (0.7537)a P = .0731 | −0.8246 (0.1509)a P < .0001 | −0.0527 (0.4779)a P = .9121 | −0.3866 (0.9531)a P = .6850 | 0.1751 (0.9150)a P = .8482 | −0.9603 (0.2290)a P < .0001 | 0.0006 (0.5753)a P = .9990 |
SURFIN | −0.3894 (0.6310)a P = .5371 | −0.0056 (0.6496)a P = .9930 | −0.5354 (0.1023)a P < .0001 | −0.2299 (0.4080)a P = .5729 | −1.8858 (1.1321)a P = .0957 | −1.1453 (0.9089)a P = .2076 | −0.6083 (0.1422)a P < .0001 | −0.0140 (0.4812)a P = .9766 |
Abbreviations: Hb, hemoglobin; PEXEL, Plasmodium export element; HT, host-targeting signal.
Regression coefficient.