Table 5.
Joint effects of hair dyes and phenotype or genotype and risk of bladder by education strata
| ALL WOMEN | NAT2 Rapid/Intermediate | NAT2 slow | ||
|---|---|---|---|---|
| Hair dye use | Ca/Co | OR* (95% CI) | Ca/Co | OR* (95% CI) |
| Never | 33/36 | Ref | 55/62 | 1.0 (0.5, 1.8) |
| Ever | 59/84 | 0.8 (0.4, 1.4) | 86/124 | 0.8 (0.4, 1.4) |
| Permanent | 27/48 | 0.6 (0.3, 1.2) | 51/61 | 0.9 (0.5, 1.6) |
| Exclusive permanent | 21/41 | 0.6 (0.3, 1.1) | 44/46 | 1.0 (0.5, 1.9) |
| WOMEN NO COLLEGE DEGREE | NAT2 Rapid/Intermediate | NAT2 slow | ||
| Never | 25/23 | Ref | 46/41 | 1.0 (0.5, 2.1) |
| Ever | 48/67 | 0.7 (0.3, 1.3) | 66/96 | 0.6 (0.3, 1.2) |
| Permanent | 20/39 | 0.4 (0.2, 1.0) | 35/49 | 0.6 (0.3, 1.3) |
| Exclusive permanent | 15/34 | 0.4 (0.2, 0.9) | 29/40 | 0.6 (0.3, 1.3) |
| WOMEN COLLEGE DEGREE | NAT2 Rapid/Intermediate | NAT2 slow | ||
| Never | 8/13 | Ref | 9/21 | 0.7 (0.2, 2.4) |
| Ever | 11/17 | 1.3 (0.4, 4.4) | 20/28 | 1.4 (0.5, 4.4) |
| Permanent | 7/9 | 1.7 (0.4, 7.0) | 16/12 | 3.1 (0.9, 11.3) |
| Exclusive permanent | 6/7 | 2.1 (0.5, 9.5) | 15/6 | 7.3 (1.6, 32.6) |
| ALL WOMEN | non NAT1*10 | any NAT1*10 | ||
| Hair dye use | ||||
| Never | 53/64 | Ref | 34/34 | 1.2 (0.7, 2.2) |
| Ever | 109/148 | 0.9 (0.6, 1.4) | 36/55 | 0.8 (0.5, 1.5) |
| Permanent | 54/74 | 0.9 (0.5, 1.5) | 24/34 | 0.8 (0.4, 1.6) |
| Exclusive permanent | 46/60 | 0.9 (0.5, 1.6) | 20/28 | 0.8 (0.4, 1.7) |
| WOMEN NO COLLEGE DEGREE | non NAT1*10 | any NAT1*10 | ||
| Never | 42/41 | Ref | 29/24 | 1.2 (0.6, 2.4) |
| Ever | 90/116 | 0.8 (0.5, 1.3) | 25/44 | 0.6 (0.3, 1.1) |
| Permanent | 40/62 | 0.6 (0.3, 1.1) | 15/27 | 0.5 (0.2, 1.1) |
| Exclusive permanent | 33/52 | 0.6 (0.3, 1.1) | 12/24 | 0.5 (0.2, 1.1) |
| WOMEN COLLEGE DEGREE | non NAT1*10 | any NAT1*10 | ||
| Never | 11/23 | Ref | 5/10 | 1.0 (0.3, 3.7) |
| Ever | 19/32 | 1.5 (0.6, 3.9) | 11/11 | 2.7 (0.8, 9.0) |
| Permanent | 14/12 | 3.0 (1.0, 9.3) | 9/7 | 3.8 (1.0, 14.9) |
| Exclusive permanent | 13/8 | 4.9 (1.4, 17.3) | 8/4 | 6.3 (1.5, 36.5) |
| ALL WOMEN | GSTM1 Any Active | GSTM1 Null | ||
| Hair dye use | ||||
| Never | 35/39 | Ref | 49/59 | 0.9 (0.5, 1.7) |
| Ever | 55/89 | 0.7 (0.4, 1.3) | 85/110 | 0.9 (0.5, 1.5) |
| Permanent | 29/37 | 0.9 (0.4, 1.7) | 48/66 | 0.8 (0.4, 1.5) |
| Exclusive permanent | 22/34 | 0.7 (0.3, 1.5) | 43/50 | 0.9 (0.5, 1.8) |
| WOMEN NO COLLEGE DEGREE | GSTM1 Any Active | GSTM1 Null | ||
| Never | 30/27 | Ref | 37/37 | 0.9 (0.5, 1.8) |
| Ever | 43/68 | 0.6 (0.3, 1.1) | 69/90 | 0.7 (0.4, 1.3) |
| Permanent | 21/32 | 0.5 (0.3, 1.2) | 35/52 | 0.6 (0.3, 1.1) |
| Exclusive permanent | 15/30 | 0.4 (0.2, 1.0) | 30/42 | 0.6 (0.3, 1.2) |
| WOMEN COLLEGE DEGREE | GSTM1 Any Active | GSTM1 Null | ||
| Never | 5/12 | Ref | 12/22 | 1.3 (0.4, 4.7) |
| Ever | 12/21 | 1.7 (0.5, 6.5) | 16/20 | 2.3 (0.6, 8.3) |
| Permanent | 8/5 | 4.6 (0.9, 22.5) | 13/14 | 2.8 (0.7, 11.2) |
| Exclusive permanent | 7/4 | 5.2 (1.0, 27.9) | 13/8 | 5.4 (1.2, 24.0) |
| ALL WOMEN | GSTT1 Any Active | GSTT1 Null | ||
| Hair dye use | ||||
| Never | 70/79 | Ref | 15/14 | 1.2 (0.5, 2.7) |
| Ever | 109/151 | 0.9 (0.6, 1.3) | 21/45 | 0.5 (0.3, 1.0) |
| Permanent | 60/81 | 0.8 (0.5, 1.3) | 10/26 | 0.4 (0.2, 1.0) |
| Exclusive permanent | 50/62 | 0.9 (0.5, 1.5) | 10/22 | 0.5 (0.2, 1.2) |
| WOMEN NO COLLEGE DEGREE | GSTT1 Any Active | GSTT1 Null | ||
| Never | 56/51 | Ref | 12/10 | 1.1 (0.4, 2.7) |
| Ever | 86/118 | 0.7 (0.4, 1.1) | 17/35 | 0.4 (0.2, 0.9) |
| Permanent | 42/66 | 0.5 (0.3, 0.9) | 8/21 | 0.3 (0.1, 0.8) |
| Exclusive permanent | 33/53 | 0.5 (0.3, 1.0) | 8/19 | 0.4 (0.1, 0.9) |
| WOMEN COLLEGE DEGREE | GSTT1 Any Active | GSTT1 Null | ||
| Never | 14/28 | Ref | 3/4 | 1.6 (0.3, 8.3) |
| Ever | 23/33 | 1.7 (0.7, 4.2) | 4/10 | 1.0 (0.3, 4.0) |
| Permanent | 18/15 | 3.3 (1.1, 9.8) | 2/5 | 1.0 (0.2, 6.2) |
| Exclusive permanent | 17/9 | 5.9 (1.7, 20.0) | 2/3 | 1.9 (0.3, 13.9) |
*
Adjusted for age, race